跳转至内容
Merck
CN

BX-0900-32

Human Microglia

new

Human iPSC line, Fully differentiated, Healthy Female Control (no known neurological disorders), Cryopreserved

别名:

Brain macrophages

登录 查看公司和协议定价

选择尺寸

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

生物来源

human (iPSC line)

表单

frozen liquid

包装

vial of 1 (contains ≥1 million cells)

技术

cell culture | mammalian: suitable

储存温度

-140 to -196°C

相关类别

一般描述

Human iPSC-Derived Microglia. Cells derived from male (BX-0900-30-1M) and female (BX-0900-32-1M) lines available. GFP-expressing neurons also available (BX-0901-30-1M). A major immune cell within the central nervous system (CNS), microglia are responsible for eliminating dead neurons, microbes, protein aggregates, and other particulates like degenerating synapses and myelin debris that are in the CNS. They also help to maintain neuronal networks, aid in injury repair, and mediate neuroinflammation. Microglia are implicated in neurodegeneration and aging, and are used to study autism, epilepsy, Alzheimer’s disease, and Huntington’s disease.

应用

Function: Human Microglia demonstrate phagocytosis and can be stimulated to secrete a variety of cytokines.

特点和优势

Marker Expression: Fully differentiated with confirmed expression of microglia surface markers including: CD45, CD11b, CX3CR1, P2RY12, and TMEM119. Immunocytochemistry shortly after plating microglia (shown here with a DAPI stain) reveals prominent expression of TREM2 (green) and IBA1 (red).

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Rezwanul Islam et al.
Translational stroke research, 16(3), 655-671 (2024-04-01)
Subarachnoid hemorrhage (SAH) accounts for 5% of stroke, with women having a decreased inflammatory response compared to men; however, this mechanism has yet to be identified. One hurdle in SAH research is the lack of human brain models. Studies in

商品

Protocol Guide: Functional Tri-Culture of iPSC-Derived Human Neurons, Astrocytes, and Microglia

Discover an expert protocol for seeding and tri-culturing iPSC-derived neurons, astrocytes, and microglia in monoculture. Explore high purity cells and culture reagents.

Protocol Guide: Cortical GABAergic Neuron Monoculture

Discover an expert protocol for seeding and culturing cortical GABAergic neurons in monoculture. Explore GABAergic neuron culture cells and reagents.

实验方案

Protocol Guide: Spiny Striatal GABAergic Neuron Monoculture

Discover an expert protocol for seeding and culturing spiny striatal GABAergic neuron in monoculture. Explore spiny GABAergic neurons and culture reagents.

Protocol Guide: Astrocytes Monoculture

Discover an expert protocol for seeding and culturing astrocytes in monoculture. Explore high purity astrocytes and culture reagents.

Protocol Guide: Cortical Glutamatergic Neuron Monoculture

Discover an expert protocol for culturing cortical glutamatergic neurons in monoculture. Explore glutamatergic neurons culture cells and reagents.

Protocol Guide: Neuron and Microglia Co-Culture Assay

Discover an expert protocol for seeding and co-culturing iPSC-derived neurons and microglia in monoculture. Explore high purity cells and culture reagents.

查看所有结果

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持