C0125
二甲基胂酸
≥98%
别名:
二甲次胂酸, 二甲胂酸, 羟基二甲基氧化胂
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线性分子式:
(CH3)2As(O)OH
化学文摘社编号:
分子量:
138.00
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-883-4
Beilstein/REAXYS Number:
1736965
MDL number:
InChI
1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)
SMILES string
C[As](C)(O)=O
InChI key
OGGXGZAMXPVRFZ-UHFFFAOYSA-N
assay
≥98%
form
powder
solubility
water: 50 mg/mL, clear, colorless
Quality Level
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
危险化学品
此项目有
Monika K Nisiewicz et al.
International journal of molecular sciences, 22(1) (2021-01-08)
Nearly half of patients with advanced and metastatic melanomas harbor a BRAF mutation. Vemurafenib (VEM), a BRAF inhibitor, is used to treat such patients, however, responses to VEM are very short-lived due to intrinsic, adaptive and/or acquired resistance. In this
Fang-Chih Chang et al.
Talanta, 198, 137-145 (2019-03-17)
An analytical method for the biomonitoring of arsenic, benzene and polycyclic aromatic hydrocarbons (PAHs) in human urine was developed using liquid chromatography tandem mass spectrometry (LC-MS/MS). The urinary metabolites of monomethylarsonic acid (MMAA), dimethylarsonic acid (DMAA), s-phenylmercapturic acid (S-PMA), and
Erik J Tokar et al.
Toxicology letters, 209(2), 179-185 (2012-01-11)
Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking
Possible carcinogenic potential of dimethylarsinic acid as assessed in rat in vivo models: a review.
S Yamamoto et al.
Mutation research, 386(3), 353-361 (1997-06-01)
The modifying effects of dimethylarsinic acid (DMA), the major metabolite of ingested arsenicals in most mammals, on chemical carcinogenesis were investigated using rat in vivo models and reviewed here. In a multi-organ bioassay, rats pretreated with 5 carcinogens were administered
Hua Naranmandura et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 137-146 (2012-04-28)
Arsenic is known to be a human carcinogen as well as one of the most effective drugs for treatment of patients with acute promyelocytic leukemia. The intermediate metabolites of arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)), are formed by
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