C0567
(-)-儿茶素
from green tea, ≥97% (HPLC), powder, oxidative stress inhibitor
别名:
(-)- 反 -3,3′,4′5,7-五羟基黄烷, (2S,3R)-2-（3,4-二羟基苯基）-3,4-二氢-1 (2H)-苯并吡喃-3,5,7-三醇
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关于此项目
经验公式（希尔记法）:
C15H14O6
化学文摘社编号:
分子量:
290.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
242-611-7
MDL number:
产品名称
(-)-儿茶素, ≥97% (HPLC), from green tea
InChI key
PFTAWBLQPZVEMU-HIFRSBDPSA-N
InChI
1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
SMILES string
O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3
biological source
green tea
assay
≥97% (HPLC)
form
powder
storage temp.
2-8°C
Quality Level
Gene Information
human ... BACE1(23621)
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Application
(-)-儿茶素已用于：
- 检测其对于雌激素受体的结合亲和力
- 作为高效液相色谱(HPLC)法定量检测植物提取物中多酚类物质的参考标准品
- 作为伊朗绿茶茶叶中抗氧化剂定量分析的动力学研究的参考标准品
Biochem/physiol Actions
儿茶素具有广泛的生物功效。它可诱发抗病毒和抗癌活性。儿茶素还在糖类和脂质代谢中起重要的调节作用。它可预防脂质积聚。
General description
儿茶素是绿茶中主要的黄酮类化合物，占比达90%。(−)-儿茶素在肠道吸收中的生物利用度相对低于(+)-儿茶素。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
(+)-Catechin is more bioavailable than (-)-catechin: relevance to the bioavailability of catechin from cocoa
Donovan JL, et al.
Free Radical Research, 40(10), 1029-1034 (2006)
Ji Hyung Jun et al.
Nature plants, 4(12), 1034-1043 (2018-11-28)
Proanthocyanidins (PAs) are primarily composed of the flavan-3-ol subunits (-)-epicatechin and/or (+)-catechin, but the basis for their different starter and extension unit compositions remains unclear. Genetic and biochemical analyses show that, in the model legume Medicago truncatula, two 2-oxoglutarate-dependent dioxygenases
Green tea catechins: Their use in treating and preventing infectious diseases
Reygaert WC
BioMed Research International, 2018 (2018)
Estrogen-like effects of wine extracts on nitric oxide synthesis in human endothelial cells
Simoncini T, et al.
Maturitas, 70(2), 169-175 (2011)
Rajapandiyan Krishnamoorthy et al.
Biomolecules, 9(12) (2019-12-11)
Human gut microbes are a profitable tool for the modification of food compounds into biologically active metabolites. The biological properties of catechins have been extensively investigated. However, the bioavailability of catechin in human blood plasma is very low. This study
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