Merck
CN
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文件

C0742

Sigma-Aldrich

CKI-7 二盐酸盐

≥98% (HPLC), solid

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别名:
N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺 二盐酸盐
经验公式（希尔记法）:
C11H12ClN3O2S · 2HCl
CAS号:
1177141-67-1
分子量:
358.67
MDL编号:
MFCD00897689
PubChem化学物质编号:
24724430
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

solid

储存条件

desiccated

颜色

white to light tan

溶解性

H2O: >5 mg/mL

储存温度

−20°C

SMILES字符串

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

生化/生理作用

CKI-7是一种CK1抑制剂；也能抑制SGK、S6K1和MSK1。 CKI-7与CK1一样能有效抑制SGK。IC50 = 6 μM。

注意

材料是吸湿性的

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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