C0742
CKI-7 二盐酸盐
≥98% (HPLC), solid, CK1 inhibitor
别名:
N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺 二盐酸盐
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关于此项目
经验公式（希尔记法）:
C11H12ClN3O2S · 2HCl
化学文摘社编号:
分子量:
358.67
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
产品名称
CKI-7 二盐酸盐, ≥98% (HPLC), solid
方案
≥98% (HPLC)
表单
solid
储存条件
desiccated
颜色
white to light tan
溶解性
H2O: >5 mg/mL
储存温度
−20°C
SMILES字符串
Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
InChI
1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H
InChI key
JUAVTXYOCISSSL-UHFFFAOYSA-N
生化/生理作用
CKI-7是一种CK1抑制剂；也能抑制SGK、S6K1和MSK1。
CKI-7是一种CK1抑制剂；也能抑制SGK、S6K1和MSK1。 CKI-7与CK1一样能有效抑制SGK。IC50 = 6 μM。
免责声明
材料是吸湿性的
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Subodh Verma et al.
The lancet. Diabetes & endocrinology, 1(4), 317-328 (2014-03-14)
The choice between coronary artery bypass surgery (CABG) and percutaneous coronary intervention (PCI) for revascularisation in patients with diabetes and multivessel coronary artery disease, who account for 25% of revascularisation procedures, is much debated. We aimed to assess whether all-cause
Masaharu Hata et al.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 190(10), 899-904 (2014-03-14)
Wide surgical excision is the standard treatment for angiosarcoma of the scalp, but many patients are inoperable. Therefore, we investigated the outcome of radiation therapy for angiosarcoma of the scalp. Seventeen patients with angiosarcoma of the scalp underwent radiation therapy
Martina Weber et al.
The American journal of clinical nutrition, 99(5), 1041-1051 (2014-03-14)
Early nutrition is recognized as a target for the effective prevention of childhood obesity. Protein intake was associated with more rapid weight gain during infancy-a known risk factor for later obesity. We tested whether the reduction of protein in infant
Sandra Krohn et al.
Journal of clinical microbiology, 52(5), 1754-1757 (2014-03-14)
Qualitative and quantitative 16S rRNA gene-based real-time PCR and direct sequencing were applied for rapid detection and identification of bacterial DNA (bactDNA) in 356 ascites samples. bactDNA was detected in 35% of samples, with a mean of 3.24 log copies
Sofia Guilherme et al.
Environmental toxicology, 30(9), 1073-1081 (2014-03-14)
Triclopyr-based herbicides are broadly used worldwide for site preparation and forest vegetation management. Thus, following application, these agrochemicals can inadvertently reach the aquatic ecosystems. Garlon(®) is one of the most popular commercial denominations of this group of herbicides, considered as
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