InChI
1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3
SMILES string
CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O
InChI key
FUPYROAFYPQUSH-UHFFFAOYSA-N
description
zwitterionic
assay
≥95.0% (HPLC)
form
solid
mol wt
399.59 Da (anhydrous)
aggregation number
≤25
technique(s)
dialysis: suitable, electrophoresis: suitable, protein quantification: suitable
Quality Level
General description
3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.
Application
C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.
Other Notes
Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Evaluation of nonionic and zwitterionic detergents as membrane protein solubilizers in two-dimensional electrophoresis
Luche S, et al.
Proteomics, 3(3), 249-253 (2003)
Yang Yang et al.
Journal of biochemistry and molecular biology, 39(2), 145-149 (2006-04-06)
To analyze the effect of Maltol on the apoptosis of Human Neuroblastoma Cells (SH-SY5Y) treated by free radical which was generated from Hydrogen Peroxide (H2O2), flow cytometry analysis on Phosphatidylserine (PS) inverting percentage was applied to determine the apoptosis. MTT
Cristina-Maria Vâlcu et al.
Proteomics, 6(14), 4166-4175 (2006-06-23)
Protein extraction from plant samples is usually challenging due to the low protein content and high level of contaminants. Therefore, the 2-DE pattern resolution is strongly influenced by the procedure of sample preparation. Efficient solubilization of proteins strictly depends on
Gabriela Julia Golebiowska et al.
Acta biochimica Polonica, 66(3), 343-350 (2019-09-12)
Two winter triticale (x Triticosecale Wittmack) model cultivars: Hewo (tolerant to pink snow mould) and Magnat (sensitive) were used to test the effect of cold-hardening (4 weeks at 4°C) on soluble ≤50 kDa protein profiles of the seedling leaves. The
Anders S Andersen et al.
The Journal of antimicrobial chemotherapy, 65(8), 1646-1654 (2010-06-15)
Commercially produced sterile green bottle fly Lucilia sericata maggots are successfully employed by practitioners worldwide to clean a multitude of chronic necrotic wounds and reduce wound bacterial burdens during maggot debridement therapy (MDT). Secretions from the maggots exhibit antimicrobial activity
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