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经验公式(希尔记法):
C9H11N3O7PNa
化学文摘社编号:
分子量:
327.16
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.77
描述
1 vial contains 50μmol or approximately 16mg
质量水平
方案
≥98% (HPLC)
表单
powder
储存温度
−20°C
SMILES字符串
[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O
InChI
1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1
InChI key
RZAHVNCNTLFRHJ-IAIGYFSYSA-M
生化/生理作用
Produced by the hydrolysis of cytidine 5′-triphosphate by the enzyme cytidylyl cyclase.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Sameer B Shah et al.
Neurobiology of disease, 36(1), 11-25 (2009-06-06)
Microtubule-based neuronal transport pathways are impaired during the progression of Alzheimer's disease and other neurodegenerative conditions. However, mechanisms leading to defects in transport remain to be determined. We quantified morphological changes in neuronal cells following treatment with fibrils and unaggregated
Xiangang Zong et al.
The Journal of biological chemistry, 287(32), 26506-26512 (2012-06-21)
Activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated in vivo by direct binding of the second messenger cAMP. This process plays a fundamental role in the fine-tuning of HCN channel activity and is critical for the modulation of cardiac
Kerstin Y Beste et al.
Biochemistry, 51(1), 194-204 (2011-11-30)
Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural and functional properties in common with adenylyl cyclases (ACs). Recently, we reported that membranous ACs and sGC are potently inhibited
Todd Michael Seib et al.
Glia, 59(10), 1387-1401 (2011-05-19)
The system x(C)- (Sx(C)-) transporter functions to mediate the exchange of extracellular cystine (L-Cys(2)) and intracellular glutamate (L-Glu). Internalized L-Cys(2) serves as a rate-limiting precursor for the biosynthesis of glutathione (GSH), while the externalized L-Glu can contribute to either excitatory
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