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经验公式(希尔记法):
C9H11N3O7PNa
化学文摘社编号:
分子量:
327.16
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
259-397-6
MDL number:
产品名称
Cytidine 3′,5′-cyclic monophosphate sodium salt, ≥98% (HPLC)
InChI key
RZAHVNCNTLFRHJ-IAIGYFSYSA-M
InChI
1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1
SMILES string
[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O
description
1 vial contains 50μmol or approximately 16mg
assay
≥98% (HPLC)
form
powder
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Produced by the hydrolysis of cytidine 5′-triphosphate by the enzyme cytidylyl cyclase.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Todd Michael Seib et al.
Glia, 59(10), 1387-1401 (2011-05-19)
The system x(C)- (Sx(C)-) transporter functions to mediate the exchange of extracellular cystine (L-Cys(2)) and intracellular glutamate (L-Glu). Internalized L-Cys(2) serves as a rate-limiting precursor for the biosynthesis of glutathione (GSH), while the externalized L-Glu can contribute to either excitatory
Kerstin Y Beste et al.
Biochemistry, 51(1), 194-204 (2011-11-30)
Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural and functional properties in common with adenylyl cyclases (ACs). Recently, we reported that membranous ACs and sGC are potently inhibited
Chika Funaki et al.
Investigative ophthalmology & visual science, 51(12), 6321-6328 (2010-07-31)
The lacrimal gland is primarily responsible for the aqueous portion of the tear film. Simultaneous addition of cholinergic agonists or growth factors with cAMP-dependent agonists potentiates secretion. Recent investigations revealed that cAMP decreases p44/p42 mitogen-activated protein kinase (MAPK) activity stimulated
Toshiaki Kume et al.
Neuroscience letters, 443(3), 199-203 (2008-08-12)
Dibutyryl cyclic AMP (dbcAMP) and retinoic acid (RA) have been demonstrated to be the inducers of morphological differentiation in SH-SY5Y cells, a human catecholaminergic neuroblastoma cell line. However, it remains unclear whether morphologically differentiated SH-SY5Y cells by these compounds acquire
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