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Merck
CN

C1006

Sigma-Aldrich

胞苷5′-单磷酸 二钠盐

Sigma Grade, ≥99%, crystalline

别名:

C-5′-P, CMP

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About This Item

线性分子式:
C9H12N3O8PNa2
CAS号:
分子量:
367.16
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

生物来源

synthetic

质量水平

等级

Sigma Grade

检测方案

≥99%

形式

crystalline

溶解性

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

储存温度

2-8°C

SMILES字符串

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O

InChI

1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;

InChI key

RCIPNLSOCXMZDD-UHFFFAOYSA-N

应用

胞苷5′-单磷酸二钠盐已用于:
  • 制备核苷酸原液
  • 作为胞外核苷酸酶(ENT酶)抑制剂探测皮层神经元中的5′-ENT酶活性
  • 在体外研究中评估其对小猪小肠内主导菌株的生长影响

生化/生理作用

胞苷5′-单磷酸(CMP)可作为尿苷单磷酸(UMP)/胞苷单磷酸(CMP)激酶(酶代码 EC 2.7.4.4)的底物形成CDP,再磷酸化形成CTP,可支持DNA和RNA的生物合成。
胞苷单磷酸(CMP)是糖类的核苷酸载体。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Charuni A Amarasekara et al.
Journal of chromatography. A, 1638, 461892-461892 (2021-01-22)
With advances in the design and fabrication of nanofluidic devices during the last decade, there have been a few reports on nucleic acid analysis using nanoscale electrophoresis. The attractive nature of nanofluidics is the unique phenomena associated with this length
Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration
Vaur P, et al.
Faseb Journal (2017)
Balvinder Dhaliwal et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 62(Pt 8), 710-715 (2006-08-02)
The crystal structure of Staphylococcus aureus cytidine monophosphate kinase (CMK) in complex with cytidine 5'-monophosphate (CMP) has been determined at 2.3 angstroms resolution. The active site reveals novel features when compared with two orthologues of known structure. Compared with the
Anaerobic growth of Bacillus mojavensis and Bacillus subtilis requires deoxyribonucleosides or DNA
Folmsbee MJ, et al.
Applied and Environmental Microbiology, 70(9) (2004)
Thomas Doneux et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 10(9-10), 1649-1655 (2009-04-07)
The interaction of cytidine 5'-monophosphate (CMP) with gold surfaces is studied by means of in situ infrared spectroscopy and cyclic voltammetry at the Au(111)|aqueous solution interface. Similar to other nucleic acid components, cytidine 5'-monophosphate is chemisorbed on the surface at

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