C102
8-Cyclopentyl-1,3-dimethylxanthine
≥98% (HPLC), powder
别名:
8-Cyclopentyltheophylline, CPT
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C12H16N4O2
化学文摘社编号:
分子量:
248.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder
InChI
1S/C12H16N4O2/c1-15-10-8(11(17)16(2)12(15)18)13-9(14-10)7-5-3-4-6-7/h7H,3-6H2,1-2H3,(H,13,14)
SMILES string
CN1C(=O)N(C)c2nc([nH]c2C1=O)C3CCCC3
InChI key
SCVHFRLUNIOSGI-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
H2O: slightly soluble <0.28 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.77 mg/mL
DMSO: ~16 mg/mL at 60 °C
0.1 M NaOH: soluble
Quality Level
Gene Information
human ... ADORA1(134)
Biochem/physiol Actions
Selective A1 adenosine receptor antagonist.
Features and Benefits
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ines Schmidts et al.
Nucleic acids research, 44(17), 8261-8271 (2016-06-30)
Small interfering RNAs (siRNAs) defend the organism against harmful transcripts from exogenous (e.g. viral) or endogenous (e.g. transposons) sources. Recent publications describe the production of siRNAs induced by DNA double-strand breaks (DSB) in Neurospora crassa, Arabidopsis thaliana, Drosophila melanogaster and
Elizabeth Shephard et al.
Cortex; a journal devoted to the study of the nervous system and behavior, 117, 96-110 (2019-04-08)
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are common and impairing neurodevelopmental disorders that frequently co-occur. The neurobiological mechanisms involved in ASD and ADHD are not fully understood. However, alterations in large-scale neural networks have been proposed as core
Huihui Chen et al.
Nature communications, 9(1), 3209-3209 (2018-08-12)
Glaucoma is the most prevalent neurodegenerative disease and a leading cause of blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not fully understood. Here we show, using mice deficient in T and/or B cells and adoptive cell transfer, that transient
Harald Schuhwerk et al.
Nucleic acids research, 45(19), 11174-11192 (2017-10-05)
One of the fastest cellular responses to genotoxic stress is the formation of poly(ADP-ribose) polymers (PAR) by poly(ADP-ribose)polymerase 1 (PARP1, or ARTD1). PARP1 and its enzymatic product PAR regulate diverse biological processes, such as DNA repair, chromatin remodeling, transcription and
Hiro Sato et al.
Nature communications, 8(1), 1751-1751 (2017-11-25)
Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but the involvement of DSB repair in PD-L1 expression has not been investigated. Here we
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持