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Merck
CN

C1105

Z-Gly-Pro-Arg 4-methoxy-2-naphthylamide trifluoroacetate salt

≥97% (HPLC), powder

别名:

Z-GPR-MNA TFA

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关于此项目

经验公式(希尔记法):
C34H40F3N7O8
分子量:
731.72
UNSPSC Code:
12352200
MDL number:
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assay

≥97% (HPLC)

form

powder

color

white

solubility

DMF or absolute ethanol: 20 mM

storage temp.

−20°C

Application

Fluorogenic substrate for granzyme A.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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M J Smyth et al.
The Journal of biological chemistry, 267(34), 24418-24425 (1992-12-05)
We have purified a 30-kDa serine protease (designated RNK-Met-1) from the granules of the rat large granular lymphocyte leukemia cell line (RNK-16) that hydrolytically cleaves model peptide substrates after methionine, leucine, and norleucine (Met-ase activity). Utilizing molecular sieve chromatography, heparin-agarose
F Velotti et al.
European journal of immunology, 22(4), 1049-1053 (1992-04-01)
Granzymes A-G are a family of serine proteases localized in the cytoplasmic granules of cytotoxic T lymphocytes (Masson, D. et al. Cell 1987. 49: 679) and granzyme A is secreted by T lymphocytes in response to antigenic stimulation. Granzyme A