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Merck
CN

C113040

DMT-dC(ac)亚磷酰胺

configured for MerMade

别名:

N-乙酰基-5′-O-[双（4-甲氧基苯基）苯基甲基] -2′-脱氧胞苷，3′-[2-氰基乙基N,N-双（1-甲基乙基）亚磷酰胺], N4-乙酰基-5′-O-（4,4′-二甲氧基三苯甲基）-2′-脱氧胞苷-3′-O-[O-（2-氰基乙基）-N,N′-二异丙基亚]

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关于此项目

经验公式（希尔记法）:
C41H50N5O8P
化学文摘社编号:
154110-40-4
分子量:
771.84
NACRES:
NA.51
PubChem Substance ID:
329774864
UNSPSC Code:
12352200
MDL number:
MFCD09842112

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产品名称

DMT-dC(ac)亚磷酰胺, configured for MerMade

InChI

1S/C41H50N5O8P/c1-28(2)46(29(3)4)55(52-25-11-23-42)54-36-26-39(45-24-22-38(43-30(5)47)44-40(45)48)53-37(36)27-51-41(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-22,24,28-29,36-37,39H,11,25-27H2,1-7H3,(H,43,44,47,48)/t36-,37+,39+,55?/m0/s1

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI key

MECWEBCHRKVTNV-RLWDVSNXSA-N

biological source

non-animal source (no BSE/TSE risk)

type

for DNA synthesis

product line

Proligo Reagents

assay

≥98% (31P-NMR)
≥99.0% (reversed phase HPLC)

form

powder

packaging

pkg of 6 × 10 g C113040-6x10G (8 oz Bottle 28-400)

technique(s)

oligo synthesis: suitable

color

white to off-white

λ

conforms (UV/VIS Identity)

compatibility

configured for MerMade

nucleoside profile

base: deoxycytidine
base protecting group: acetyl
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard

storage temp.

-10 to -25°C

Quality Level

200

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相关类别

General description

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. DMT-dC(ac) Phosphoramidite is an acetyl-protected DNA phosphoramidite used in fast deprotection chemistry for the rapid and high-yield synthesis of high-purity oligonucleotides. Key Features of dC(ac):
  • Ultrafast deprotection: 10 minutes at 65°C with AMA reagent
  • Key component in oligonucleotide synthesis
  • Industry-standard for fast deprotection chemistry
  • Operating for AMA deprotection methods without changes
  • Consistent lot-to-lot high purity and performance
  • Manufactured under a certified ISO 9001 quality systemThe product belongs to MerMade synthesizers.

Packaging

C113040-6x5G packaged in a 8 oz bottle with a 28-400 cap
C113040-6x10G packaged in a 8 oz bottle with a 28-400 cap

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
HMBK7507
HMBK7024
HMBK6894
HMBK6860
HMBK4919

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