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Merck
CN

C1131

胞苷 5′-一磷酸

≥99% (HPLC), synthetic, powder

别名:

5′-CMP, 5′-胞苷酸, C-5′-P

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关于此项目

经验公式（希尔记法）:
C9H14N3O8P
化学文摘社编号:
63-37-6
分子量:
323.20
NACRES:
NA.51
PubChem Substance ID:
24892358
UNSPSC Code:
41106305
EC Number:
200-556-6
MDL number:
MFCD00006544
Beilstein/REAXYS Number:
46982
Assay:
≥99% (HPLC)
Biological source:
synthetic
Form:
powder
Solubility:
1 M NH4OH: 50 mg/mL, clear, colorless
Storage temp.:
2-8°C

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产品名称

胞苷 5′-一磷酸, Sigma Grade, ≥99% (HPLC), synthetic, powder

InChI key

IERHLVCPSMICTF-XVFCMESISA-N

InChI

1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O

biological source

synthetic

grade

Sigma Grade

assay

≥99% (HPLC)

form

powder

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

storage temp.

2-8°C

Quality Level

200

相关类别

Application

胞苷5′-单磷酸已用于拉曼光谱研究。

Biochem/physiol Actions

核苷二磷酸胞苷二磷酸(CDP)和尿苷二磷酸(UDP)是合成嘧啶的必需组分胞苷5′-单磷酸(CMP)核苷酸用于仿生磷灰石的吸附研究，用于模拟骨骼矿物质。它也可用作儿科制剂中的免疫增强剂。
胞苷5′-单磷酸 (CMP) 作为单磷酸尿苷 (UMP)/单磷酸胞苷 (CMP) 激酶（酶代码 EC 2.7.4.4）的底物形成 CDP，CDP 经磷酸化形成 CTP，支持 DNA 和 RNA 的生物合成。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000519723
0000519723
0000509982
0000509987
0000509982

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Brendon Stubbs et al.
Geriatrics & gerontology international, 15(7), 881-888 (2014-08-29)
Chronic musculoskeletal pain (CMP) and falls are common among community-dwelling older adults. The study aims were: (i) to investigate the relationship between CMP and any falls (≥1), single falls and recurrent falls (≥2) in community-dwelling older adults; and (ii) to
A Hirono et al.
British journal of haematology, 65(1), 35-41 (1987-01-01)
Human erythrocyte pyrimidine 5'-nucleotidase (P5N) was separated into two subclasses. P5N-I and P5N-II, by DEAE Bio-Gel A column chromatography. Their enzymological properties were studied using five normal subjects and five patients with different P5N deficiencies. Study of the normal subjects
Adsorption of nucleotides on biomimetic apatite: The case of cytidine 5? monophosphate (CMP)
Choimet M, et al.
Journal of Colloid and Interface Science, 456, 132-137 (2015)
An enzymatic alternative for the synthesis of nucleoside 5?-monophosphates
Gudino ED, et al.
Enzyme and Microbial Technology, 111, 1-6 (2018)
Riku Aono et al.
Journal of bacteriology, 194(24), 6847-6855 (2012-10-16)
AMP phosphorylase (AMPpase), ribose-1,5-bisphosphate (R15P) isomerase, and type III ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) have been proposed to constitute a novel pathway involved in AMP metabolism in the Archaea. Here we performed a biochemical examination of AMPpase and R15P isomerase from Thermococcus
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实验方案

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

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