C1145
胆固醇-PEG 600
别名:
水溶性胆固醇 来源于绵羊, 癸二酸聚氧乙基胆甾醇酯, 聚乙二醇 600 单（胆固醇）醚癸二酸酯, 胆固醇-聚乙二醇 600 癸二酸酯
表单
solid
标记范围
≥20% cholesterol
颜色
light yellow
溶解性
H2O: 60 mg/mL
运输
dry ice
储存温度
−20°C
一般描述
胆固醇是所有膜的重要组分之一。它是由一个极性羟基基团、平面的稠环核和一条短链烃尾组成的疏水分子。
应用
胆固醇-PEG 600已用于评估其诱导血管平滑肌细胞凋亡的能力。本品可在甲基β-环糊精消除后再度恢复胆固醇。
生化/生理作用
胆固醇是类固醇激素的前体。它在胎儿生长与大脑发育中起重要作用。
外形
半固体至固体
制备说明
采用 Proksch,G.J. 和 Bonderman,D.P. 的方法制备，Clin. Chem., 24, 1924 (1978).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Disruption of cholesterol homeostasis in developmental neurotoxicity
Reproductive and Developmental Toxicology null
Linda Shaw et al.
Cardiovascular research, 69(4), 825-835 (2006-02-09)
A close association of caveolae and sarcoplasmic reticulum (SR) has been suggested to be important for contractile activation of smooth muscle. Here, we investigate the presence of such arrangements in pressurised resistance arteries and examine the influence of two agents
Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SKCa channels and caveolin-rich domains
Absi M, et al.
British Journal of Pharmacology, 332-340, 332-340 null
M Absi et al.
British journal of pharmacology, 151(3), 332-340 (2007-04-24)
The small and intermediate conductance, Ca2+-sensitive K+ channels (SK(Ca) and IK(Ca), respectively) which are pivotal in the EDHF pathway may be differentially activated. The importance of caveolae in the functioning of IK(Ca) and SK(Ca) channels was investigated. The effect of
The Lipids of Biological Membranes
The Membranes of Cells null
商品
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