C1145
胆固醇-PEG 600
别名:
水溶性胆固醇 来源于绵羊, 癸二酸聚氧乙基胆甾醇酯, 聚乙二醇 600 单（胆固醇）醚癸二酸酯, 胆固醇-聚乙二醇 600 癸二酸酯
form
solid
extent of labeling
≥20% cholesterol
color
light yellow
solubility
H2O: 60 mg/mL
shipped in
dry ice
storage temp.
−20°C
Quality Level
Application
胆固醇-PEG 600已用于评估其诱导血管平滑肌细胞凋亡的能力。本品可在甲基β-环糊精消除后再度恢复胆固醇。
Biochem/physiol Actions
胆固醇是类固醇激素的前体。它在胎儿生长与大脑发育中起重要作用。
General description
胆固醇是所有膜的重要组分之一。它是由一个极性羟基基团、平面的稠环核和一条短链烃尾组成的疏水分子。
Physical form
半固体至固体
Preparation Note
采用 Proksch,G.J. 和 Bonderman,D.P. 的方法制备，Clin. Chem., 24, 1924 (1978).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Apoptosis of vascular smooth muscle cells induced by cholesterol and its oxides in vitro and in vivo
Yin J, et al.
Atherosclerosis, 148(2), 365-374 (2000)
The Lipids of Biological Membranes
The Membranes of Cells null
M Absi et al.
British journal of pharmacology, 151(3), 332-340 (2007-04-24)
The small and intermediate conductance, Ca2+-sensitive K+ channels (SK(Ca) and IK(Ca), respectively) which are pivotal in the EDHF pathway may be differentially activated. The importance of caveolae in the functioning of IK(Ca) and SK(Ca) channels was investigated. The effect of
Linda Shaw et al.
Cardiovascular research, 69(4), 825-835 (2006-02-09)
A close association of caveolae and sarcoplasmic reticulum (SR) has been suggested to be important for contractile activation of smooth muscle. Here, we investigate the presence of such arrangements in pressurised resistance arteries and examine the influence of two agents
Disruption of cholesterol homeostasis in developmental neurotoxicity
Reproductive and Developmental Toxicology null
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