C1244
CHM-1 hydrate
≥99% (HPLC), solid
别名:
2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
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关于此项目
经验公式（希尔记法）:
C16H10FNO3 · xH2O
化学文摘社编号:
分子量:
283.25 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥99% (HPLC)
Form:
solid
Storage condition:
desiccated
assay
≥99% (HPLC)
form
solid
storage condition
desiccated
solubility
DMSO: ≥5 mg/mL
storage temp.
2-8°C
SMILES string
O.Fc1ccccc1C2=CC(=O)c3cc4OCOc4cc3N2
InChI
1S/C16H10FNO3.H2O/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12;/h1-7H,8H2,(H,18,19);1H2
InChI key
KIAVGSCBJYDTIM-UHFFFAOYSA-N
Biochem/physiol Actions
CHM-1 possess antimitotic and antiangiogenic antitumor activity.
CHM-1 possess antimitotic,antiangiogenic and antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.
Features and Benefits
This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)