C125
(±)-CGP-12177A
≥98% (HPLC), solid
别名:
(±)-CGP-12177 hydrochloride, 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1, 3-dihydro-2H-benzimidazol-2-one hydrochloride
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关于此项目
经验公式（希尔记法）:
C14H21N3O3 · HCl
化学文摘社编号:
分子量:
315.80
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: >10 mg/mL
SMILES string
Cl.CC(C)(C)NCC(O)COc1cccc2NC(=O)Nc12
InChI
1S/C14H21N3O3.ClH/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10;/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19);1H
InChI key
YQVFCYCTITZLSX-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
Application
(±)-CGP-12177A has been used as a β-Adrenergic receptor agonist:
- to evaluate the dissociation constant (Kd) by frontal affinity chromatography
- to study its cardiostimulant effects on rat ventricular cardiomyocytes
- to study its binding affinity in α1D-adrenoceptors expressed in rat BHK-21 cells
Biochem/physiol Actions
β-adrenoceptor nonconventional partial agonist.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)