Complement C7 deficiencies in humans are rare, but often associated with recurrent infections by Neisseria spp. (such as meningitis). C7 deficiencies in patients with meningococcal meningitis have shown a mutation which results in an 11 bp deletion in exon 6 resulting in a premature stop codon. Additionally, research has suggested that screening of patients with systemic neisserial infection by CH50 or the APH-50 assay can reveal a C7 deficiency.

Supplied as a solution in PBS, pH 7.4

C7 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.