C144
1-（3-氯苯基）双胍 盐酸盐
solid
别名:
1-（间氯苯基）双胍 盐酸盐, N-（3-氯苯基）亚氨基二碳亚胺二酰胺 盐酸盐, m-CPBG 盐酸盐
表单
solid
颜色
white
mp
190-194 °C (lit.)
溶解性
H2O: soluble
SMILES字符串
Cl[H].NC(=N)NC(=N)Nc1cccc(Cl)c1
InChI
1S/C8H10ClN5.ClH/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11;/h1-4H,(H6,10,11,12,13,14);1H
InChI key
FOWAIJYHRWFTHR-UHFFFAOYSA-N
基因信息
human ... HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242)
正在寻找类似产品? 访问 产品对比指南
生化/生理作用
非常强效的5-HT35-羟色胺受体激动剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Reza Rahimian et al.
Brain research, 1392, 101-109 (2011-03-31)
Tropisetron is widely used to counteract chemotherapy-induced emesis. Evidence obtained from human and animal studies shows that tropisetron possesses anti-inflammatory properties. In this study, we assessed the effect of tropisetron on brain damage in a rat thromboembolic model of stroke.
Gohar Fakhfouri et al.
Human & experimental toxicology, 29(4), 321-328 (2010-02-16)
Inflammatory bowel disease (IBD) is a chronically relapsing inflammation of the gastrointestinal tract, of which the definite etiology remains ambiguous. Considering the adverse effects and incomplete efficacy of currently administered drugs, it is indispensable to explore new candidates with more
Arash Bahremand et al.
Epilepsy & behavior : E&B, 21(2), 122-127 (2011-05-03)
Citalopram, a selective serotonin reuptake inhibitor (SSRI), is frequently used in the treatment of major depressive disorders. In addition to its antidepressant features, citalopram shows some anticonvulsive properties at lower doses, whereas higher doses, ingested in cases of suicide, have
Philip M Lang et al.
Journal of neurophysiology, 96(6), 2963-2971 (2006-09-08)
Activity-dependent fluctuations in axonal excitability and changes in interspike intervals modify the conduction of trains of action potentials in unmyelinated peripheral nerve fibers. During inflammation of a nerve trunk, long stretches of axons are exposed to inflammatory mediators such as
Jaime M Monti et al.
Progress in neuro-psychopharmacology & biological psychiatry, 35(5), 1341-1348 (2011-04-26)
The effects of the selective 5-HT(3) receptor agonist m-chlorophenylbiguanide (m-CPBG), and of the NMDA (N-methyl-D-aspartate) and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionate)/kainate antagonists AP-5 [(±)-2-amino-5-phosphono-pentanoic acid] and CNQX (6-cyano-7-nitroquinoxaline-2,3-dione), respectively, were studied in adult male Wistar rats implanted for chronic sleep recordings. The
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持