C1530
Cyclopiazonic acid
from Penicillium cyclopium, ≥98% (HPLC), powder, sarcoplasmic reticulum Ca²⁺-pump inhibitor
别名:
CPA
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C20H20N2O3
化学文摘社编号:
分子量:
336.38
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
环盐酸吗甲吡嗪酸 来源于圆弧青霉菌, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: soluble, chloroform: soluble
storage temp.
−20°C
SMILES string
CN1C(=O)C(=C(\C)O)\C(=O)C2C(Cc3cccc4[nH]cc2c34)C1(C)C
InChI
1S/C20H22N2O3/c1-10(23)15-18(24)17-12-9-21-14-7-5-6-11(16(12)14)8-13(17)20(2,3)22(4)19(15)25/h5-7,9,13,17,21,23H,8H2,1-4H3/b15-10-
InChI key
WJCPGKDPOYBOOJ-GDNBJRDFSA-N
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA3(140)
mouse ... Adora1(11539)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)
General description
圆弧偶氮酸（CPA）是由多种 曲霉 和 青霉菌 种合成的tetramic酸。
Application
圆弧青霉菌来源圆弧偶氮酸用于：
- 作为标准品，用于薄层色谱法（TLC）检测和定量黄曲霉毒素
- 作为培养基成分，用于不含Ca2+的DMEM（含10％胎牛血清（FBS））
- 作为肌质网/内质网Ca2+ -ATP酶的可逆抑制剂，检测腔内钙在内质网（ER）-至-高尔基体转运过程中的作用
- 作为内质网Ca2+-ATP酶的阻滞剂，处理神经元；研究内质网（ER）在Ca2+诱导的Ca2+ 释放（CICR）抑制 SERCA 过程中，对释放和维持Ca2+ 的影响
Biochem/physiol Actions
抑制肌质网 Ca 2 + -泵。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Toxigenic Aspergillus flavus and other fungi of public health concern in food and organic matter in southwest Nigeria
Fapohunda SO, et al.
Mycology, 3, 210-219 (2012)
Ca2+-Induced Ca2+ Release in Aplysia Bag Cell Neurons Requires Interaction Between Mitochondrial and Endoplasmic Reticulum Stores
Geiger JE, et al.
Journal of Neurophysiology (2008)
N Demaurex et al.
The Journal of biological chemistry, 267(4), 2318-2324 (1992-02-05)
The filling state of intracellular Ca2+ stores has been proposed to regulate Ca2+ influx across the plasma membrane in a variety of tissues. To test this hypothesis, we have used three structurally unrelated inhibitors of the Ca(2+)-ATPase of intracellular Ca2+
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C1530-10MG | 04061833467701 |
| C1530-50MG | 04061833269510 |
| C1530-5MG | 04061833467718 |