C1625
L-刀豆氨酸
≥98% (TLC), powder, from Canavalia ensiformis
别名:
L-α-氨基-γ-（胍氧基）-n-丁酸
产品名称
L-刀豆氨酸, ≥98% (TLC), powder, from Canavalia ensiformis
生物来源
Canavalia ensiformis
质量水平
方案
≥98% (TLC)
表单
powder
颜色
white to yellow
溶解性
H2O: <100 mg/mL
应用
detection
储存温度
2-8°C
SMILES字符串
N[C@@H](CCONC(N)=N)C(O)=O
InChI
1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1
InChI key
FSBIGDSBMBYOPN-VKHMYHEASA-N
生化/生理作用
一种天然存在的 L -氨基酸，由于其结构相似性而干扰 L -精氨酸利用酶。它是诱导型一氧化氮合酶 (iNOS) 的选择性抑制剂。iNOS 产生过量的 NO 在脓毒性休克和慢性炎症的病理生理过程中起角色至关重要的作用。
刀豆氨酸是一种天然存在的 L-氨基酸，由于其结构相似性，可干扰 L-精氨酸利用酶。它是诱导型一氧化氮合酶 (iNOS) 的选择性抑制剂。iNOS 产生过量的 NO 在脓毒性休克和慢性炎症的病理生理过程中起角色至关重要的作用。
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
E Arthur Bell
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 10 Suppl 2, 21-25 (2009-12-16)
Because of the similarity of ALS/PDC symptoms to those of the paralytic disease lathyrism, cycad seeds from Guam were analyzed for the presence of the non-protein amino acid b-ODAP, which is known to cause lathyrism. Although b-ODAP was not detected
Nayun Kim et al.
Science (New York, N.Y.), 332(6037), 1561-1564 (2011-06-28)
The ribonuclease (RNase) H class of enzymes degrades the RNA component of RNA:DNA hybrids and is important in nucleic acid metabolism. RNase H2 is specialized to remove single ribonucleotides [ribonucleoside monophosphates (rNMPs)] from duplex DNA, and its absence in budding
Nami Haruta et al.
Nucleic acids research, 40(17), 8406-8415 (2012-06-30)
UV radiation induces two major types of DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine-pyrimidine photoproducts, which are both primarily repaired by nucleotide excision repair (NER). Here, we investigated how chronic low-dose UV (CLUV)-induced mutagenesis occurs in rad14Δ NER-deficient
Matthew D Berg et al.
G3 (Bethesda, Md.), 10(12), 4335-4345 (2020-10-22)
Non-proteinogenic amino acids, such as the proline analog L-azetidine-2-carboxylic acid (AZC), are detrimental to cells because they are mis-incorporated into proteins and lead to proteotoxic stress. Our goal was to identify genes that show chemical-genetic interactions with AZC in Saccharomyces
Ya-Lan Chang et al.
Antioxidants & redox signaling, 22(7), 587-602 (2014-10-21)
Mitochondrial succinate dehydrogenase (SDH) is an essential complex of the electron transport chain and tricarboxylic acid cycle. Mutations in the human SDH subunit D frequently lead to paraganglioma (PGL), but the mechanistic consequences of the majority of SDHD polymorphisms have
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