C2196
L-半胱氨酸S-硫酸盐
≥98% (TLC), suitable for ligand binding assays
别名:
S-磺基-L-半胱氨酸
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关于此项目
经验公式（希尔记法）:
C3H7NO5S2
化学文摘社编号:
分子量:
201.22
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
1726832
产品名称
L-半胱氨酸S-硫酸盐, ≥98% (TLC)
InChI
1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
SMILES string
N[C@@H](CSS(O)(=O)=O)C(O)=O
InChI key
NOKPBJYHPHHWAN-REOHCLBHSA-N
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white
storage temp.
−20°C
Quality Level
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Biochem/physiol Actions
L-半胱氨酸硫酸盐（LCSS）被用作NMDA谷氨酸能受体激动剂。 它可作为胱氨酸裂解酶的底物。
半胱氨酸是与生长、繁殖、维持和免疫相关的功能性氨基酸之一。半胱氨酸是蛋白质中二硫键的来源，与硫转运有关。在生理pH下，半胱氨酸经过快速氧化，形成胱氨酸。半胱氨酸或胱氨酸的可用性降低将影响白细胞代谢。L-半胱氨酸是神经元中谷胱甘肽合成过程的限速步骤的前体。它可提供无机硫酸盐，用于解毒反应。因此，L-半胱氨酸可能与神经保护有关。已有研究发现它能阻止重金属离子穿过血脑屏障进入大脑。L-半胱氨酸水平升高可能导致神经毒性。
半胱氨酸是与生长、繁殖、维持和免疫相关的功能性氨基酸之一。半胱氨酸是蛋白质中二硫键的来源，与硫转运有关。在生理pH下，半胱氨酸经过快速氧化，形成胱氨酸。半胱氨酸或胱氨酸的可用性降低将影响白细胞代谢。L-半胱氨酸是神经元中谷胱甘肽合成过程的限速步骤的前体。它可提供无机硫酸盐，用于解毒反应。因此，L-半胱氨酸可能与神经保护有关。已有研究发现它能阻止重金属离子穿过血脑屏障进入大脑。L-半胱氨酸水平升高可能导致神经毒性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Mechanisms of L-Cysteine Neurotoxicity
R. Janaky
Neurochemical Research, 25, 1397-1405 (2000)
Cecilia Gotor et al.
Plant signaling & behavior, 5(8), 1028-1030 (2010-08-12)
The cysteine molecule plays an essential role in cells because it is part of proteins and because it functions as a reduced sulfur donor molecule. In addition, the cysteine molecule may also play a role in the redox signaling of
L H Ngu et al.
Singapore medical journal, 50(10), e365-e367 (2009-11-13)
Molybdenum cofactor deficiency is a rare autosomal recessive disorder with devastating neurological manifestations, characterised by neonatal-onset encephalopathy mimicking hypoxic-ischaemic insult, intractable seizure, and feeding and respiratory difficulties. It is often fatal in the early life. We report an affected 8-year-old
Emma E Hobson et al.
European journal of pediatrics, 164(11), 655-659 (2005-07-19)
Isolated sulphite oxidase deficiency (ISOD) is a rare autosomal recessive inborn error of metabolism, which may present at birth with intractable seizures (often of prenatal onset) and severe neurological abnormalities. In infants who survive, lens dislocation may occur from 8
Claus Jacob et al.
Angewandte Chemie (International ed. in English), 42(39), 4742-4758 (2003-10-17)
Sulfur and selenium occur in proteins as constituents of the amino acids cysteine, methionine, selenocysteine, and selenomethionine. Recent research underscores that these amino acids are truly exceptional. Their redox activity under physiological conditions allows an amazing variety of posttranslational protein
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