C2230
天然腔肠素
solid
别名:
3,2-二氢-2-（对羟基苄基）-6-（对羟基苯基）-8-苄基咪唑并 \ [1,2-a] 吡嗪-3-酮, CLZN
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关于此项目
经验公式（希尔记法）:
C26H21N3O3
化学文摘社编号:
分子量:
423.46
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32
方案
≥95% (TLC)
表单
solid
溶解性
methanol and ethanol: soluble
储存温度
−20°C
SMILES字符串
Oc1ccc(CC2=NC3=C(Cc4ccccc4)NC(=CN3C2=O)c5ccc(O)cc5)cc1
InChI
1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
InChI key
YHIPILPTUVMWQT-UHFFFAOYSA-N
一般描述
腔肠素是萤光素分子，可被多种萤光素酶利用，如 海肾属、刺虾属 和绿叶水母中存在的荧光素酶。
应用
天然腔肠素用于：
- 水母发光蛋白测定
- 在 COS-7 细胞中使用水母发光蛋白测量离子霉素或 PMA 诱导的细胞内钙离子浓度
- 在生物发光成像中分析病毒依赖性荧光素酶活性的存在
生化/生理作用
当 Ca 2 + 与复合物结合时，水母发光蛋白复合物的发光基团被氧气氧化并在 465 nm 处发光；用于测量细胞内 Ca 2 + 浓度，灵敏度高，动态范围大。
水母发光蛋白复合物的发光基团用于测量 Ca 2 + 浓度。
免责声明
避免光照
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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