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文件

C231

CGP-20712A methanesulfonate salt

Name: CGP-20712A methanesulfonate salt
Brand: SIGMA

solid, ≥98% (HPLC)

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别名:

(±)-2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl] amino]ethoxy]-benzamide methanesulfonate salt

经验公式（希尔记法）:

C₂₃H₂₅F₃N₄O₅ · CH₄O₃S

CAS号:

105737-62-0

分子量:

590.57

MDL编号:

MFCD00798870

PubChem化学物质编号:

24278787

NACRES:

NA.77

检测方案

≥98% (HPLC)

形式

solid

储存条件

desiccated

颜色

white to off-white

溶解性

H₂O: >10 mg/mL
DMSO: 100 mg/mL

储存温度

2-8°C

SMILES字符串

CS(O)(=O)=O.Cn1cc(nc1-c2ccc(OCC(O)CNCCOc3ccc(O)c(c3)C(N)=O)cc2)C(F)(F)F

InChI

1S/C23H25F3N4O5.CH4O3S/c1-30-12-20(23(24,25)26)29-22(30)14-2-4-16(5-3-14)35-13-15(31)11-28-8-9-34-17-6-7-19(32)18(10-17)21(27)33;1-5(2,3)4/h2-7,10,12,15,28,31-32H,8-9,11,13H2,1H3,(H2,27,33);1H3,(H,2,3,4)

InChI key

VFPOVCXWKBYDNF-UHFFFAOYSA-N

基因信息

human ... ADRB1(153)

应用

CGP-20712A methanesulfonate salt has been used as a β1-adrenergic receptor antagonist in adult rat ventricular myocytes (ARVM) and rat cardiac fibroblasts. It may also be used as an antagonist for the β1-adrenergic receptor in rat bladder smooth muscles.

生化/生理作用

CGP-20712A methanesulfonate salt is a selective β1-adrenoceptor antagonist.

注意

Product is hygroscopic

法律信息

Sold exclusively with the permission of Ciba-Geigy.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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A Ferro et al.

Journal of cardiovascular pharmacology, 25(1), 134-141 (1995-01-01)

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