Name: 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N

CAS Number:

276696-61-8

分子量:

605.07

MDL编号:

MFCD04037247

UNSPSC代码:

41106305

PubChem化学物质编号:

329775000

NACRES:

NA.77

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生物来源

synthetic

方案

≥98% (HPLC)

表单

solid

颜色

white

溶解性

H₂O: 5 mg/mL

储存温度

−20°C

SMILES字符串

CCN(CC)CC.NC1=Nc2c(nc(Sc3ccc(Cl)cc3)n2[C@@H]4O[C@@H]5CO[P@@](O)(=S)O[C@H]5[C@H]4O)C(=O)N1

InChI

1S/C16H15ClN5O6PS2.C6H15N/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(27-14)5-26-29(25,30)28-11;1-4-7(5-2)6-3/h1-4,8,10-11,14,23H,5H2,(H,25,30)(H3,18,20,21,24);4-6H2,1-3H3/t8-,10-,11-,14-,29-;/m1./s1

InChI key

KVOYZBYGWGWWTD-TXBWCVORSA-N

生化/生理作用

Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II.

特点和优势

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

联系

8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine.