产品名称
5β-胆甾烷-3α-醇, ≥95%
InChI
1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20-,21-,22+,23-,24+,25+,26+,27-/m1/s1
SMILES string
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI key
QYIXCDOBOSTCEI-KKFSNPNRSA-N
assay
≥95%
form
powder
shipped in
ambient
storage temp.
room temp
Quality Level
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Application
采用 5β-胆甾烷-3α-醇作为内标物，通过 GC 和 HPLC 分析血浆中的固醇。
Biochem/physiol Actions
5β-胆甾烷-3α-醇是胆固醇内源性生成的固醇，已从人和大鼠粪便中分离得到。它是由胆固醇经肠道微生物作用而得。
Preparation Note
5β-胆甾烷-3α-醇在 50 mg/mL 氯仿中生成澄清、无色至淡黄色溶液。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Anna N Bukiya et al.
The Journal of general physiology, 137(1), 93-110 (2010-12-15)
The activity (Po) of large-conductance voltage/Ca(2+)-gated K(+) (BK) channels is blunted by cholesterol levels within the range found in natural membranes. We probed BK channel-forming α (cbv1) subunits in phospholipid bilayers with cholesterol and related monohydroxysterols and performed computational dynamics
D Blache et al.
Journal of chromatography. B, Biomedical sciences and applications, 702(1-2), 103-110 (1998-02-04)
Resveratrol is a trihydroxystilbene present in certain red wines. It may play a role in the inhibition of lipoprotein oxidation and platelet activity. We have developed the first method to measure resveratrol in animal and human samples and to study
Quantitative analysis of sterols in serum by high-performance liquid chromatography: application to the biochemical diagnosis of cerebrotendinous xanthomatosis
Kasama T et al
Journal of Chromatography A, 400, 241-246 (1987)
M Souidi et al.
Life sciences, 64(17), 1585-1593 (1999-06-03)
Our purpose was to examine the in vitro modulation of liver mitochondrial sterol 27-hydroxylase (S27OHase) and microsomal cholesterol 7alpha-hydroxylase (CH7alphaOHase) activities by certain drugs, sterols, oxysterols and bile acids, and to compare the influence of sex, age, diet and cholestyramine
Vikaskumar G Shah et al.
Water research, 41(16), 3691-3700 (2007-07-07)
Faecal samples from humans, herbivores, carnivores and birds as well as samples from septic tanks and effluents from a sewage treatment plant (STP) were extracted and analyzed by gas chromatography-mass spectrometry for faecal sterols including coprostanol, epicoprostanol, cholestanol, cholesterol, stigmasterol
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