C2969
Monoclonal Anti-I-CAM-1 (CD54) antibody produced in mouse
clone 8.4A6, purified immunoglobulin
别名:
Monoclonal Anti-CD54, Anti-I-CAM-1
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关于此项目
Conjugate:
unconjugated
Clone:
8.4A6, monoclonal
Application:
ELISA (i), FACS, ICC, IHC (f)
Citations:
1
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
8.4A6, monoclonal
mol wt
antigen 85-110 kDa
species reactivity
human, monkey
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry (frozen sections): suitable, indirect ELISA: suitable
isotype
IgG1
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ICAM1(3383)
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General description
CD54 (I-CAM-1) is a glycoprotein involved in mediation of intercellular adhesion. CD54 is expressed by activated endothelial cells and is also detected on cells of many other lineages and in plasma.
Immunogen
TNF-α activated human endothelial cells.
Biochem/physiol Actions
The antibody recognizes the human CD54 (I-CAM-1) surface antigen by flow cytometry, ELISA, immunocytochemistry, and immunohistochemistry. It inhibits human leukocyte adhesion to activated endothelial cells and stimulates homotypic aggregation of SKW3 cells. The epitope recognized by the antibody is localized in domain D2 of the CD54 molecule.
5th Workshop: code no. S 100
5th Workshop: code no. S 100
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4.
Preparation Note
Product filtered through a 0.2 μm filter
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
法规信息
新产品
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Lanlan Tang et al.
Oncotarget, 8(16), 27314-27327 (2017-04-14)
Differentiation therapy based on all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) for the treatment of acute promyelocytic leukemia (APL) is complicated by the development of differentiation syndrome (DS), which can be fatal. We examined the role of HMGB1 (high-mobility group
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