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Merck
CN

C3025

(±)-氯苯那敏 马来酸盐

≥99% (perchloric acid titration)

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关于此项目

经验公式(希尔记法):
C16H19ClN2 · C4H4O4
化学文摘社编号:
分子量:
390.86
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
204-037-5
MDL number:
Assay:
≥99% (perchloric acid titration)
Form:
powder
Quality level:
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Quality Level

assay

≥99% (perchloric acid titration)

form

powder

mp

130-135 °C (lit.)

originator

Bayer

SMILES string

CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

DBAKFASWICGISY-BTJKTKAUSA-N

Gene Information

human ... HRH1(3269)

General description

马来酸氯苯吡胺(CPM)/(3-(4-氯苯基)-N,N-二甲基-3-吡啶-2-基-丙烷-1-胺是一种烷基胺抗组胺药。

Application

(±)-马来酸氯苯吡胺已被用于:
  • 作为H1受受体拮抗剂用于测定受体功能
  • 阻断化合物48/80对血浆IGF-I的作用
  • 作为标准品通过配有电位差计的顺序进样器用于快速感应和测定

Biochem/physiol Actions

马来酸氯苯吡胺(CPM)可预防鼻炎和荨麻疹。它常用于治疗多种过敏症状。这种抗组胺药也用于小动物的兽医治疗。
H 1 组胺受体拮抗剂。

Features and Benefits

该化合物由Bayer开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Liao W, et al.
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Zhang L, et al.
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Functionalized Fe3O4 Magnetic Nanoparticle Potentiometric Detection Strategy versus Classical Potentiometric Strategy for Determination of Chlorpheniramine Maleate and Pseudoephedrine HCl
Moustafa AA, et al.
Journal of Analytical Methods in Chemistry (2019)
V Alagarsamy et al.
European journal of medicinal chemistry, 43(11), 2331-2337 (2007-11-23)
A series of novel 1-substituted-4-(2-methylphenyl)-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones were synthesized by the cyclization of 2-hydrazino-3-(2-methylphenyl)-3H-quinazolin-4-one with various one carbon donors. The starting material 2-hydrazino-3-(2-methylphenyl)-3H-quinazolin-4-one was synthesized from 2-methyl aniline by a novel innovative route. The title compounds were tested for their in vivo

全球贸易项目编号

货号GTIN
C3025-5G04061833485163
C3025-100G04061835259588
C3025-25G04061833485156

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