主要文件

查看所有文档

C3394

虫草素

Name: 虫草素
Brand: SIGMA

from Cordyceps militaris, ≥98% (HPLC), powder, adenosine analogue

别名:

3′-脱氧腺苷

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₀H₁₃N₅O₃

化学文摘社编号:

73-03-0

分子量:

251.24

NACRES:

NA.77

PubChem Substance ID:

24892611

UNSPSC Code:

12352200

EC Number:

200-791-4

MDL number:

MFCD00037998

Beilstein/REAXYS Number:

35194

Form:

powder

Quality level:

200

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

虫草素, from Cordyceps militaris

biological source

Cordyceps militaris

Quality Level

200

form

powder

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits, DNA synthesis | interferes

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)C[C@H]3O

InChI

1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1

InChI key

OFEZSBMBBKLLBJ-BAJZRUMYSA-N

Gene Information

rat ... Adora1(29290)

正在寻找类似产品? 访问产品对比指南

General description

化学结构：核苷

Biochem/physiol Actions

虫草素是一种腺苷类似物，易于转化为5′-三磷酸虫草素；可用于RNA的3′-端标记。

Features and Benefits

该化合物是受体分类及信号转导手册上腺苷酸环化酶页面上的特色化合物。想要浏览手册的其他页面，请单击此处。

该化合物是环核苷酸和基因调控研究的特色产品。发现更多环核苷酸和基因调控特色产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。

pictograms

GHS06

signalword

Danger

hcodes

H301 + H311 + H331

pcodes

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000488199

0000467763

0000455818

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells.

E N Kodama et al.

Biochemical pharmacology, 59(3), 273-281 (1999-12-28)

The nucleoside analogue cordycepin (3'-deoxyadenosine, 3'-dA) is substantially more cytotoxic to terminal deoxynucleotidyl transferase positive (TdT+) leukemic cells than to TdT leukemic cells in vitro in the presence of an adenosine deaminase inhibitor, deoxycoformycin (dCF), and has been considered as

Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways.

Ying-Yi Chen et al.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(8-9), 768-778 (2012-04-03)

Cancer metastasis is a primary cause of cancer death. Antrodia cinnamomea (A. cinnamomea), a medicinal mushroom in Taiwan, has been shown antioxidant and anticancer activities. In this study, we first observed that ethanol extract of fruiting bodies of A. cinnamomea

A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.

Guifen Wu et al.

Cell reports, 30(7), 2387-2401 (2020-02-23)

Degradation of transcripts in human nuclei is primarily facilitated by the RNA exosome. To obtain substrate specificity, the exosome is aided by adaptors; in the nucleoplasm, those adaptors are the nuclear exosome-targeting (NEXT) complex and the poly(A) (pA) exosome-targeting (PAXT) connection.

Changes in mRNA stability associated with cold stress in Arabidopsis cells.

Yukako Chiba et al.

Plant & cell physiology, 54(2), 180-194 (2012-12-12)

Control of mRNA half-life is a powerful strategy to adjust individual mRNA levels to various stress conditions, because the mRNA degradation rate controls not only the steady-state mRNA level but also the transition speed of mRNA levels. Here, we analyzed

Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.

Suman K Vodnala et al.

Journal of medicinal chemistry, 56(24), 9861-9873 (2013-11-29)

Novel methods for treatment of African trypanosomiasis, caused by infection with Trypanosoma brucei are needed. Cordycepin (3'-deoxyadenosine, 1a) is a powerful trypanocidal compound in vitro but is ineffective in vivo because of rapid metabolic degradation by adenosine deaminase (ADA). We

查看所有相关文献

商品

Discover Bioactive Molecules for Nucleotides

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

全球贸易项目编号

货号	GTIN
C3394-100MG	04061833269787
C3394-10MG	04061835555925
C3394-25MG	04061833485767

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持