C3412
醋酸环丙孕酮
≥98%
别名:
6-Chloro-1β,2β-dihydro-17-hydroxy-3′H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate
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关于此项目
经验公式（希尔记法）:
C24H29ClO4
化学文摘社编号:
分子量:
416.94
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
207-048-3
MDL number:
Assay:
≥98%
Form:
powder
Quality Segment
assay
≥98%
form
powder
storage temp.
2-8°C
SMILES string
[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C
InChI
1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1
InChI key
UWFYSQMTEOIJJG-FDTZYFLXSA-N
Gene Information
human ... AR(367), NR3C1(2908), PGR(5241)
mouse ... Nr3c1(14815)
rat ... Ar(24208)
Application
Cyproterone acetate has been used to study its effects on insulin-like growth factor I secretion.
Biochem/physiol Actions
Cyproterone acetate is a synthetic steroid and an androgen antagonist. It is a potent inhibitor of leukocyte migration through endothethial cell monolayers. Cyproterone acetate acts as a liver tumor promoter in experimental animal model. Liver tumor promotion appears to be female gender-specific, as formation of an active metabolite that forms DNA adducts.
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges