InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h10,18-21,23-25,28H,6-9,11-17H2,1-5H3/t19-,20+,21?,23?,24?,25?,26?,27?/m1/s1
SMILES string
CC(CCC[C@@H](C)[C@@](CC[C@]1(C2=CC[C@@]3([H])C[C@@](O)(CC[C@]43C)[H])[H])([C@]1(CC[C@@]24[H])C)[H])C
InChI key
IZVFFXVYBHFIHY-IRRCOBOTSA-N
assay
≥98% (TLC)
form
powder
shipped in
ambient
storage temp.
−20°C
Quality Level
Application
5α-胆甾-7-烯-3β-醇被用作酶法测定血浆胆固醇的底物。它还被作为饲料添加剂，以研究其对 盔型溞 生活史性状的影响。
Biochem/physiol Actions
5α-胆甾-7-烯-3β-是胆固醇生物合成途径的中间体。血清中的甾醇由脂蛋白携带，并指示胆固醇合成速率。它作为胆固醇合成的标记物，不受饮食摄入胆固醇的影响。
Preparation Note
5α-胆甾-7-烯-3β-醇在氯仿中生成澄清、无色溶液，浓度为 10 mg/mL。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
G S Tint et al.
Journal of lipid research, 15(3), 256-262 (1974-05-01)
The metabolism of Delta(7)-cholestenol, cholesterol, and cholestanol was examined in a patient with cerebrotendinous xanthomatosis after intravenous pulse-labeling with a mixture of dl-[2-(14)C]mevalonate and stereospecific 3S,4S,3R,4R-[4-(3)H]mevalonate. Silver nitrate and reversed-phase thin-layer chromatography were used to purify the sterols isolated from
Matthew G K Benesch et al.
Biochemistry, 50(46), 9982-9997 (2011-09-29)
We performed differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopic measurements to study the effects of lathosterol (Lath) on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine (DPPC) bilayer membranes and compared our results with those previously reported
Y H Han et al.
Biological & pharmaceutical bulletin, 23(10), 1247-1249 (2000-10-21)
From the butanol fraction of the starfish Asterina pectinifera Müler et Troschel (Asteriidae), we have isolated a new component, 5alpha-cholest-7-en-3beta-ol. Its antigenotoxic and antimutagenic activities were examined by the SOS chromotest with Escherichia coli PQ37 and by Ames test with
Artyom Kopp
Current biology : CB, 22(23), R1004-R1006 (2012-12-12)
Host-plant specialization plays a key role in insect evolution, but little is known about its molecular basis. A new paper shows that a cactus-feeding fly became restricted to its host by changes in an enzyme that converts dietary sterols into
A Rahier
Biochemistry, 40(1), 256-267 (2001-01-05)
Deuterium-labeled 5alpha-cholest-7-en-3beta-ol (1) bearing one or two deuteriums at the C-5alpha and (or) C-6alpha positions was synthesized in high isotopic and chiral purity. These compounds were used as substrates with the microsomal wild-type Zea mays and recombinant Arabidopsis thaliana Delta(7)-sterol-C5(6)-desaturases
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