C3930
钙调蛋白抑制剂
solid
别名:
1- [双（4-氯苯基）甲基]-3- [2,4-二氯-β-氯化咪唑, 1- [双（4-氯苯基）甲基]-3- [2-（2,4-二氯苯基）-2-（2,4-二氯苄氧基）乙基]-1H-咪唑氯化物, R 24571
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关于此项目
经验公式（希尔记法）:
C31H23Cl7N2O
化学文摘社编号:
分子量:
687.70
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6470244
form
solid
color
white
InChI
1S/C31H23Cl6N2O.ClH/c32-23-6-1-20(2-7-23)31(21-3-8-24(33)9-4-21)39-14-13-38(19-39)17-30(27-12-11-26(35)16-29(27)37)40-18-22-5-10-25(34)15-28(22)36;/h1-16,19,30-31H,17-18H2;1H/q+1;/p-1
SMILES string
[Cl-].Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3
InChI key
YGEIMSMISRCBFF-UHFFFAOYSA-M
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
钙调素调节酶抑制剂。它也被认为可以直接阻断平滑肌细胞的钙通道。
Preparation Note
可用 DMSO 制备 5 mM 储备液，然后用缓冲液稀释至 0.01 mM。DMSO 溶液可储存数周。
Disclaimer
在水溶液中与玻璃表面结合。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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American journal of physiology. Heart and circulatory physiology, 301(2), H428-H433 (2011-05-17)
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The Biochemical journal, 430(1), 39-48 (2010-06-10)
The HMG (high-mobility group)-box-containing chromatin-remodelling factor SRY (sex-determining region on the Y chromosome) plays a key role in sex determination. Its role in the nucleus is critically dependent on two NLSs (nuclear localization signals) that flank its HMG domain: the
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