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Merck
CN

C4186

Cytochrome c partially acetylated from equine heart

lyophilized powder

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关于此项目

UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Form:
lyophilized powder
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form

lyophilized powder

composition

Protein, ~90% E0.1%/550

extent of labeling

~60% acetylated lysine residues (based on ninhydrin assay)

solubility

H2O: soluble 10 mg/mL, clear, red to red-brown

storage temp.

−20°C

Quality Level

Application

The enzyme has been used for the measuring superoxide production using the superoxide dismutase-inhibitable (SOD-inhibitable) cytochrome c reduction assay.

Packaging

Package size based on protein content.

Physical form

Contains potassium phosphate buffer salts.

Preparation Note

Dissolves in water to form a clear, red-brown colored solution at 10 mg/mL concentration.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

动植物来源生物产品
此项目有

历史批次信息供参考:

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Heidi C O'Neill et al.
Antioxidants & redox signaling, 10(2), 277-285 (2007-12-27)
Lipoic acid (LA) and its reduced product dihydrolipoic acid (DHLA) are potent antioxidants with capacity to scavenge reactive oxygen species (ROS) and recycle endogenous antioxidants. LA may increase cellular glutathione (GSH), an antioxidant lacking in the lung's epithelial lining fluid
The use of acetylated ferricytochrome c for the detection of superoxide radicals produced in biological membranes.
A Azzi et al.
Biochemical and biophysical research communications, 65(2), 597-603 (1975-07-22)
Carsten Wunderlich et al.
Pulmonary pharmacology & therapeutics, 21(3), 507-515 (2008-01-30)
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Ulf Landmesser et al.
The Journal of clinical investigation, 111(8), 1201-1209 (2003-04-17)
Tetrahydrobiopterin is a critical cofactor for the NO synthases, and in its absence these enzymes become "uncoupled," producing reactive oxygen species (ROSs) rather than NO. In aortas of mice with deoxycorticosterone acetate-salt (DOCA-salt) hypertension, ROS production from NO synthase is
Maria Simitsopoulou et al.
Methods in molecular medicine, 118, 161-179 (2005-05-13)
Candida albicans and non-albicans Candida spp. can cause serious infections in hospitalized and immunocompromised patients. A large number of antifungal agents and immunomodulators have been developed and may interact with both polymorphonuclear and mononuclear phagocytes against blastoconidia and pseudohyphae of

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