C4375
N-氨基甲酰-L-谷氨酸
≥98.0% (TLC)
别名:
N-(aminocarbonyl)-L-glutamic acid
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关于此项目
经验公式（希尔记法）:
C6H10N2O5
化学文摘社编号:
分子量:
190.15
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
N-氨基甲酰-L-谷氨酸,
SMILES string
NC(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
InChI key
LCQLHJZYVOQKHU-VKHMYHEASA-N
assay
≥98.0% (TLC)
form
powder
color
white
application(s)
cell analysis
storage temp.
2-8°C
Quality Level
Gene Information
human ... CPS1(1373)
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Biochem/physiol Actions
N-氨基甲酰-L-谷氨酸（氨甲酰谷氨酸）被用于研究其作为替代疗法对N-乙酰谷氨酸合成酶（NAGS）缺乏症的治疗潜力，并用于治疗高氨血症。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
X Wu et al.
Journal of animal science, 90 Suppl 4, 337-339 (2013-02-13)
To evaluate the effects of glutamate (Glu) or combination of Glu and N-carbamylglutamate (NCG) on intestinal mucosa morphology and epithelium cell proliferation, 18 piglets weaned at 21 d (BW 5.56 ± 0.51 kg) were grouped into 3 treatments and fed
X Wu et al.
Animal reproduction science, 132(3-4), 187-192 (2012-06-12)
The objectives of this study were to investigate the potential mechanisms of dietary arginine (Arg) and N-carbamoylglutamate (NCG) supplementation on reproductive performance of sows. Twenty-seven crossbred (Landrace×Large White) sows with similar body weight and parity at day (90±1) of gestation
Boris Gebhardt et al.
Molecular genetics and metabolism, 79(4), 303-304 (2003-09-02)
In patients with methylmalonic aciduria (MMA), the accumulating metabolite propiony-CoA results in an inhibition of the urea circle via the decreased synthesis of N-acetylglutamate, an essential activator of carbamylphosphat synthetase (CPS). This results in one of the major clinical problems
X D Liu et al.
Amino acids, 42(6), 2111-2119 (2011-06-04)
Placental vascular formation and blood flow are crucial for fetal survival, growth and development, and arginine regulates vascular development and function. This study determined the effects of dietary arginine or N-carbamylglutamate (NCG) supplementation during late gestation of sows on the
Nicholas Ah Mew et al.
Molecular genetics and metabolism, 98(4), 325-330 (2009-08-08)
We studied the effect on ureagenesis of a single dose of N-carbamylglutamate (NCG) in healthy young adults who received a constant infusion (300 min) of NaH(13)CO(3). Isotope ratio-mass spectrometry was used to measure the appearance of label in [(13)C]urea. At
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