C4375
N-氨基甲酰-L-谷氨酸
≥98.0% (TLC)
别名:
N-(aminocarbonyl)-L-glutamic acid
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关于此项目
经验公式（希尔记法）:
C6H10N2O5
化学文摘社编号:
分子量:
190.15
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
N-氨基甲酰-L-谷氨酸,
assay
≥98.0% (TLC)
Quality Level
form
powder
color
white
application(s)
cell analysis
storage temp.
2-8°C
SMILES string
NC(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
InChI key
LCQLHJZYVOQKHU-VKHMYHEASA-N
Gene Information
human ... CPS1(1373)
Biochem/physiol Actions
N-氨基甲酰-L-谷氨酸（氨甲酰谷氨酸）被用于研究其作为替代疗法对N-乙酰谷氨酸合成酶（NAGS）缺乏症的治疗潜力，并用于治疗高氨血症。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
B Gebhardt et al.
Journal of inherited metabolic disease, 28(2), 241-244 (2005-05-07)
In patients with propionic aciduria, the accumulating metabolite propionyl-CoA causes a disturbance of the urea cycle via the inhibition of N-acetylglutamate synthesis. Lack of this allosteric activator results in an inhibition of carbamoylphosphate synthase (CPS). This finally leads to hyperammonaemia.
Nicolas Gauthier et al.
PloS one, 8(7), e60581-e60581 (2013-07-19)
Most conditions detected by expanded newborn screening result from deficiency of one of the enzymes that degrade acyl-coenzyme A (CoA) esters in mitochondria. The role of acyl-CoAs in the pathophysiology of these disorders is poorly understood, in part because CoA
Xin Wu et al.
Amino acids, 39(3), 831-839 (2010-03-10)
This study determined effects of dietary supplementation with L-arginine (Arg) or N-carbamylglutamate (NCG) on intestinal health and growth in early-weaned pigs. Eighty-four Landrace x Yorkshire pigs (average body weight of 5.56+/-0.07 kg; weaned at 21 days of age) were fed
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C4375-10G | 04061833492031 |