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Merck
CN

C4375

Sigma-Aldrich

N-氨基甲酰-L-谷氨酸

≥98.0% (TLC)

别名:

N-(aminocarbonyl)-L-glutamic acid

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关于此项目

经验公式(希尔记法):
C6H10N2O5
化学文摘社编号:
分子量:
190.15
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
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产品名称

N-氨基甲酰-L-谷氨酸,

方案

≥98.0% (TLC)

表单

powder

颜色

white

应用

cell analysis

储存温度

2-8°C

SMILES字符串

NC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1

InChI key

LCQLHJZYVOQKHU-VKHMYHEASA-N

基因信息

human ... CPS1(1373)

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生化/生理作用

N-氨基甲酰-L-谷氨酸(氨甲酰谷氨酸)被用于研究其作为替代疗法对N-乙酰谷氨酸合成酶(NAGS)缺乏症的治疗潜力,并用于治疗高氨血症。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Virginie Levrat et al.
Orphanet journal of rare diseases, 3, 2-2 (2008-02-01)
Hyperammonemia in patients with methylmalonic aciduria (MMA) and propionic aciduria (PA) is caused by accumulation of propionyl-CoA which decreases the synthesis of N-acetyl-glutamate, the natural activator of carbamyl phosphate synthetase 1. A treatment approach with carglumic acid, the structural analogue
X D Liu et al.
Amino acids, 42(6), 2111-2119 (2011-06-04)
Placental vascular formation and blood flow are crucial for fetal survival, growth and development, and arginine regulates vascular development and function. This study determined the effects of dietary arginine or N-carbamylglutamate (NCG) supplementation during late gestation of sows on the
Nicholas Ah Mew et al.
Molecular genetics and metabolism, 98(4), 325-330 (2009-08-08)
We studied the effect on ureagenesis of a single dose of N-carbamylglutamate (NCG) in healthy young adults who received a constant infusion (300 min) of NaH(13)CO(3). Isotope ratio-mass spectrometry was used to measure the appearance of label in [(13)C]urea. At
X Wu et al.
Journal of animal science, 90 Suppl 4, 337-339 (2013-02-13)
To evaluate the effects of glutamate (Glu) or combination of Glu and N-carbamylglutamate (NCG) on intestinal mucosa morphology and epithelium cell proliferation, 18 piglets weaned at 21 d (BW 5.56 ± 0.51 kg) were grouped into 3 treatments and fed
X Wu et al.
Animal reproduction science, 132(3-4), 187-192 (2012-06-12)
The objectives of this study were to investigate the potential mechanisms of dietary arginine (Arg) and N-carbamoylglutamate (NCG) supplementation on reproductive performance of sows. Twenty-seven crossbred (Landrace×Large White) sows with similar body weight and parity at day (90±1) of gestation

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