一般描述
含腺嘌呤的柠檬酸盐-磷酸盐-葡萄糖溶液 (CPDA) 是一种用于储存血液的抗凝剂和防腐剂。可将红细胞保存期限延长至 35 天。维持血小板活性。使用 CPDA 可提高输血后可视性，改善血液中的葡萄糖和 ATP 水平。
应用
含腺嘌呤的柠檬酸盐-磷酸盐-葡萄糖溶液已被用作心脏穿刺采血过程中的抗凝剂， 转基因鸡蛋溶菌酶-卵清蛋白-Duffy (HOD) 小鼠 和人类。
生化/生理作用
可用于全血的抗凝
建议的抗凝血剂:全血比为 1:9
建议的抗凝血剂:全血比为 1:9
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
HyunJoo Park et al.
Scientific reports, 6, 34257-34257 (2016-10-05)
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various
Krishnan MohanKumar et al.
Nature communications, 10(1), 3494-3494 (2019-08-04)
Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this
Comparison of equine platelet function and survival in whole blood collected in acid-citrate-dextrose solution or citrate-phosphate-dextrose-adenine solution
Bozorgmanesh R, et al.
Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology, 46(2), 262-268 (2017)
The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1)
Beutler E and West C
Blood, 54(1), 280-284 (1979)
Taesik Go et al.
Scientific reports, 10(1), 8977-8977 (2020-06-04)
Digital holographic microscopy enables the recording of sample holograms which contain 3D volumetric information. However, additional optical elements, such as partially or fully coherent light source and a pinhole, are required to induce diffraction and interference. Here, we present a
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