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线性分子式:
C10H13N5 · CH3SO3H
化学文摘社编号:
分子量:
299.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
产品名称
9-Cyclopentyladenine monomethanesulfonate, ≥98% (HPLC)
InChI
1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)
SMILES string
CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3
InChI key
AJMDRSJHCYQPQI-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
mp
180-183 °C (lit.)
solubility
H2O: 5 mg/mL, clear
storage temp.
room temp
Quality Level
Biochem/physiol Actions
A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain.
A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
wgk
WGK 3
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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