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Merck
CN

C4805

β-环糊精

powder, BioReagent, suitable for cell culture, ≥97%

别名:

Schardinger β-Dextrin, 环七淀粉, 环糊精, 环麦芽七糖

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关于此项目

经验公式(希尔记法):
C42H70O35
化学文摘社编号:
分子量:
1134.98
UNSPSC Code:
12352201
NACRES:
NA.77
PubChem Substance ID:
EC Number:
231-493-2
Beilstein/REAXYS Number:
78623
MDL number:
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InChI key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

sterility

non-sterile

product line

BioReagent

assay

≥97%

form

powder

optical activity

[α]20/D +162±3°, c = 1.5% in H2O

technique(s)

cell culture | mammalian: suitable

mp

290-300 °C (dec.) (lit.)

solubility

1 M NaOH: 50 mg/mL

shipped in

ambient

storage temp.

room temp

Quality Level

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Application

ββ-环糊精(β-CD)已用于合成单-6-对甲苯磺酰-CD。它还作为无血清培养基组分,用于评估大鼠嗜碱性白血病细胞吞噬纳米颗粒涉及的(细胞膜)胆固醇依赖机制。

Biochem/physiol Actions

ββ-环糊精是葡萄糖的环状α七聚物。它可形成包合物容纳多种组分,包括苯衍生物、环己烷、金刚烷、其他脂环族以及无机分子或离子。它常用于溶解非极性化合物,如脂肪酸、脂质和胆固醇。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Synthesis of mono-6-tosyl-beta-cyclodextrin, a key intermediate for the functional cyclodextrin derivatives
Tan T, et al.
Protocol Exchange (2011)
Space filling of beta-cyclodextrin and beta-cyclodextrin derivatives by volatile hydrophobic guests
Fourmentin S, et al.
Beilstein Journal of Organic Chemistry, 9(1), 1185-1191 (2013)
Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles
Ekkapongpisit M, et al.
International journal of nanomedicine, 7, 1829-1829 (2012)
Hanane Messiad et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 21-27 (2013-03-30)
Piceatannol is one of resveratrol derivatives having health promoting potential. However, its low water-solubility and bioavailability could limit its use in both food and pharmaceutical fields. The aim of this work is the study of piceatannol complexation by β-cyclodextrin (β-CD)
Xu Zhang et al.
Chemical communications (Cambridge, England), 49(8), 825-827 (2012-12-14)
This work revealed that β-cyclodextrin was attached onto the surface of TiO(2) predominately by its secondary ring side, which caused paradoxical functions of β-cyclodextrin in the photodegradation of the four bisphenols. The equilibrium between the guest adsorbed through β-cyclodextrin onto

商品

Cyclodextrin solubilizes fat-soluble vitamins and hormones, enhancing their solubility in water for cell culture applications.

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

How palmitic acid, other fatty acids and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

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