C5020
头孢唑啉 钠盐
89.1-110.1%
别名:
Cefazoline sodium, Monosodium cefazolin
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关于此项目
经验公式（希尔记法）:
C14H13N8NaO4S3
化学文摘社编号:
分子量:
476.49
UNSPSC Code:
51282532
NACRES:
NA.76
PubChem Substance ID:
EC Number:
248-278-4
Beilstein/REAXYS Number:
3585038
MDL number:
Quality Level
assay
89.1-110.1%
form
powder
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)s1
InChI
1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1
InChI key
FLKYBGKDCCEQQM-WYUVZMMLSA-M
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General description
Chemical structure: β-lactam
Biochem/physiol Actions
Used to study the effect of expression, binding and inhibition of penicillin-binding proteins, especially PBP2 and PBP4 on bacterial cell wall mucopeptide synthesis.
Preparation Note
Freely soluble in water, very slightly soluble in chloroform and ethanol.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
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Pharmacokinetic studies and therapeutic drug monitoring of antibiotics require a simple, rapid, and reliable analytical method for monitoring the concentrations in plasma, including unbound concentrations for highly protein-bound drugs. The aim of the current work was to develop and validate
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Journal of peptide science : an official publication of the European Peptide Society, 23(10), 777-789 (2017-07-15)
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Antimicrobial agents and chemotherapy, 57(3), 1283-1290 (2013-01-01)
The increasing resistance of bacteria to conventional antibiotics and the challenges posed by intracellular bacteria, which may be responsible for chronic and recurrent infections, have driven the need for advanced antimicrobial drugs for effective elimination of both extra- and intracellular
Kevin E Chan et al.
Journal of the American Society of Nephrology : JASN, 23(9), 1551-1559 (2012-08-21)
Staphylococcus bacteremia is a common and life-threatening medical emergency, but it is treatable with appropriate antibiotic therapy. To identify opportunities that may reduce morbidity and mortality associated with S. aureus, we analyzed data from 293,094 chronic hemodialysis outpatients to characterize
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C5020-1G | 04061833501627 |
| C5020-100MG | 04061833501610 |
| C5020-500MG | 04061833501634 |
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