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Merck
CN

C5157

菜油甾醇

~65%

别名:

24α-甲基-5-胆固烯-3β-醇, 24(R)-Ergost-5-en-3β-ol

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关于此项目

经验公式（希尔记法）:
C28H48O
化学文摘社编号:
474-62-4
分子量:
400.68
UNSPSC Code:
12352211
NACRES:
NA.28
PubChem Substance ID:
24892762
EC Number:
207-484-4
Beilstein/REAXYS Number:
3216975
MDL number:
MFCD00010475

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产品名称

菜油甾醇, ~65%

InChI key

SGNBVLSWZMBQTH-ZRUUVFCLSA-N

InChI

1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1

SMILES string

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CC[C@H](C)C(C)C

biological source

Glycine max (soybean)

form

powder

concentration

~65%

shipped in

ambient

storage temp.

−20°C

Quality Level

200

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Analysis Note

通过HPLC和GC分析得到二氢菜子甾醇（24β-甲基-5-胆甾烯-3β-醇；24[S]-麦角甾-5-烯-3β-醇）的含量约为98%，但 13C-NMR显示含量约为35％。

Application

在对植物来源的油样品进行GC 和HPLC 分析时，菜油甾醇被用作标准品。

Biochem/physiol Actions

植物甾醇。可降低膳食胆固醇的吸收。
菜油甾醇是一种植物甾醇，主要存在于坚果、水果、豆类和种子中。虽然它是胆固醇的类似物，但它在人体中的吸收很差，并且能够竞争性抑制胆固醇的吸收。菜油甾醇降低了参与肝细胞和肠细胞中胆固醇代谢的基因的转录，并且对心血管疾病的治疗具有积极影响。

Preparation Note

菜油甾醇以20mg/ml浓度溶于氯仿，可得到透明、无色至淡黄色的溶液。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000370711
0000370712
0000367950
0000367951
0000352125

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Dunford NT and King JW
Journal of Food Science, 65, 1395-1399 (2000)
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Journal of ginseng research, 41(3), 428-433 (2017-07-14)
In this study, the fermentation of ginseng seeds was hypothesized to produce useful physiologically-active substances, similar to that observed for fermented ginseng root. Ginseng seed was fermented using The ginseng seed was fermented inoculating 1% of each strain on sterilized
Hannu Päivä et al.
Clinical pharmacology and therapeutics, 78(1), 60-68 (2005-07-09)
Myopathy, probably caused by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in skeletal muscle, rarely occurs in patients taking statins. This study was designed to assess the effect of high-dose statin treatment on cholesterol and ubiquinone metabolism and mitochondrial function in human skeletal
Juan P Barrios-Ramos et al.
Journal of the science of food and agriculture, 92(11), 2349-2357 (2012-03-21)
The effect of functional foods alone or in combination (cocoa + soy + oats + fish oil) on hepatic damage in rats affected with metabolic syndrome was investigated. Rats that were given cocoa showed a decrease in the levels of
Kang Jiang et al.
Journal of the American Society for Mass Spectrometry, 30(9), 1700-1712 (2019-05-22)
Phytosterols and tocopherols are essential for plant biochemistry, and they possess beneficial health effects for humans. Evaluating the tandem mass spectrometric (MS/MS) behavior of phytosterols and tocopherols is needed for the development of a qualitative and quantitative method for these
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Product Information Sheet - C5157

Product Information Sheet

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