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C5259

Carbamyl-β-methylcholine chloride

Name: Carbamyl-β-methylcholine chloride
Brand: SIGMA

≥99% (TLC), crystalline

别名:

Bethanechol chloride

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关于此项目

线性分子式:

C₇H₁₇N₂O₂Cl

化学文摘社编号:

590-63-6

分子量:

196.68

NACRES:

NA.25

PubChem Substance ID:

24277823

UNSPSC Code:

41116107

EC Number:

209-686-8

MDL number:

MFCD00055224

Assay:

≥99% (TLC)

Form:

crystalline

Quality level:

100

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属性

Quality Level

100

assay

≥99% (TLC)

form

crystalline

color

white

solubility

H₂O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)

storage temp.

2-8°C

SMILES string

Cl.CC(C[N](C)(C)C)OC(N)=O

InChI

1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H

InChI key

AIRHOJQHGLTTTB-UHFFFAOYSA-N

说明

General description

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.

Disclaimer

Hygroscopic.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Adult and Pediatric Urology, 1, 1127-1127 (2002)

Generation of a human urinary bladder smooth muscle cell line.

Zheng Y, Chang S, Boopathi E, et al.

In Vitro Cellular & Developmental Biology, 48, 84-96 (2012)

Role of acetylcholinesterase in airway epithelium-mediated inhibition of acetylcholine-induced contraction of guinea-pig isolated trachea.

Y Koga et al.

European journal of pharmacology, 220(2-3), 141-146 (1992-09-22)

To seek evidence for the involvement of acetylcholinesterase activity in the modulatory influence of the airway epithelium, we examined responses to acetylcholine (ACh), bethanechol, histamine or KCl in isolated epithelium-intact and epithelium-denuded guinea-pig trachealis preparations. The concentration-response curves to ACh

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全球贸易项目编号

货号	GTIN
C5259-5G	04061833501900
C5259-100G	04061832861913