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C5259

Carbamyl-β-methylcholine chloride

Name: Carbamyl-β-methylcholine chloride
Brand: SIGMA

≥99% (TLC), crystalline

别名:

Bethanechol chloride

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关于此项目

线性分子式:

C₇H₁₇N₂O₂Cl

化学文摘社编号:

590-63-6

分子量:

196.68

NACRES:

NA.25

PubChem Substance ID:

24277823

UNSPSC Code:

41116107

EC Number:

209-686-8

MDL number:

MFCD00055224

Assay:

≥99% (TLC)

Form:

crystalline

Quality level:

100

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属性

Quality Level

100

assay

≥99% (TLC)

form

crystalline

color

white

solubility

H₂O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)

storage temp.

2-8°C

SMILES string

Cl.CC(C[N](C)(C)C)OC(N)=O

InChI

1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H

InChI key

AIRHOJQHGLTTTB-UHFFFAOYSA-N

说明

General description

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.

Disclaimer

Hygroscopic.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function.

Jagmohan Singh et al.

Gastroenterology, 143(5), 1308-1318 (2012-08-07)

Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function. The disorder has been associated with circulating antibodies to cholinergic muscarinic the type-3 receptor (M(3)-R). We investigated whether it is possible to neutralize these antibodies with pooled human

Adult and Pediatric Urology, 1, 1127-1127 (2002)

Anti-ulcerogenic mechanisms of the sesquiterpene lactone onopordopicrin-enriched fraction from Arctium lappa L. (Asteraceae): role of somatostatin, gastrin, and endogenous sulfhydryls and nitric oxide.

Ana Beatriz Albino de Almeida et al.

Journal of medicinal food, 15(4), 378-383 (2011-12-24)

Arctium lappa L. has been used in folk medicine as a diuretic, depurative, and digestive stimulant and in dermatological conditions. The mechanisms involved in the anti-ulcerogenic activity of the sesquiterpene onopordopicrin (ONP)-enriched fraction (termed the ONP fraction), obtained from A.

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全球贸易项目编号

货号	GTIN
C5259-5G	04061833501900
C5259-100G	04061832861913