Quality Level
assay
≥99% (TLC)
form
crystalline
color
white
solubility
H2O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)
storage temp.
2-8°C
SMILES string
Cl.CC(C[N](C)(C)C)OC(N)=O
InChI
1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
InChI key
AIRHOJQHGLTTTB-UHFFFAOYSA-N
General description
Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.
Application
Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.
Biochem/physiol Actions
Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.
Disclaimer
Hygroscopic.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jagmohan Singh et al.
Gastroenterology, 143(5), 1308-1318 (2012-08-07)
Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function. The disorder has been associated with circulating antibodies to cholinergic muscarinic the type-3 receptor (M(3)-R). We investigated whether it is possible to neutralize these antibodies with pooled human
Adult and Pediatric Urology, 1, 1127-1127 (2002)
Ana Beatriz Albino de Almeida et al.
Journal of medicinal food, 15(4), 378-383 (2011-12-24)
Arctium lappa L. has been used in folk medicine as a diuretic, depurative, and digestive stimulant and in dermatological conditions. The mechanisms involved in the anti-ulcerogenic activity of the sesquiterpene onopordopicrin (ONP)-enriched fraction (termed the ONP fraction), obtained from A.
Munenori Nagao et al.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 16(2), 334-343 (2011-11-08)
Our aim was to determine mechanisms of action of the gasotransmitter hydrogen sulfide (H(2)S) on contractile activity in circular muscle of rat jejunum. Jejunal circular muscle strips were prepared to measure isometric contractions. Effects of sodium hydrosulfide (NaHS), a H(2)S
Generation of a human urinary bladder smooth muscle cell line.
Zheng Y, Chang S, Boopathi E, et al.
In Vitro Cellular & Developmental Biology, 48, 84-96 (2012)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C5259-100G | 04061832861913 |
| C5259-5G | 04061833501900 |
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