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Merck
CN

C5608

Sigma-Aldrich

胶原 来源于兔皮肤

Bornstein and Traub Type I, powder

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EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.61
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生物来源

rabbit skin

质量水平

描述

acid soluble

表单

powder

技术

cell culture | stem cell: suitable

溶解性

aqueous acid: ≤10 mg/mL
aqueous sodium acetate buffer: soluble (0.01-0.5M)

UniProt登记号

储存温度

2-8°C

基因信息

rabbit ... COL1A2(100008997)

一般描述

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

应用

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.

Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

制备说明

Prepared with modification of Gallop, P.M.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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