表单
powder
溶解性
1 M NaOH: 50 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
储存温度
2-8°C
SMILES字符串
COC(=O)N\N=C\c1cn(=O)c2ccccc2n1=O
InChI
1S/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+
InChI key
OVGGLBAWFMIPPY-WUXMJOGZSA-N
应用
卡巴多司已被用于抑制醛固酮的产生，研究产生志贺毒素的大肠杆菌（STEC）菌株的传播，以及比较不同的抗菌活性。
生化/生理作用
卡巴多司是一种喹喔啉二氧化氮抗生素，通常用在猪饲料中预防痢疾并提高饲料效率。它通过插入和诱导细菌基因组中的突变来抑制细菌。
其他说明
保存于密闭容器内，置于干燥通风处。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 1B - Flam. Sol. 1
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
WGK 3
闪点(°F)
64.4 °F - closed cup
闪点(°C)
18 °C - closed cup
M C Walsh et al.
Journal of animal science, 90(8), 2599-2608 (2012-02-22)
The objective of this study was to evaluate the effects of water-delivered, direct-fed microbials (DFM) or organic acids on intestinal morphology and active nutrient absorption in weanling pigs after deliberate Salmonella infection. Pigs (n = 88) were weaned at 19
Amisha D Shah et al.
Environmental science & technology, 40(23), 7228-7235 (2006-12-22)
The potential release of carbadox (CDX), a commonly used antibacterial agent in swine husbandry, into water systems is of a concern due to its carcinogenic and genotoxic effects. Until this study, the reactivity of carbadox (possessing quinoxaline N,N'-dioxide and hydrazone
Torey Looft et al.
Frontiers in microbiology, 5, 276-276 (2014-06-25)
Antibiotics are used in livestock and poultry production to treat and prevent disease as well as to promote animal growth. Carbadox is an in-feed antibiotic that is widely used in swine production to prevent dysentery and to improve feed efficiency.
T Hayashi et al.
Antimicrobial agents and chemotherapy, 32(4), 458-461 (1988-04-01)
Sedecamycin (lankacidin A), one of the lankacidin-group antibiotics, showed potent activity against Treponema hyodysenteriae. The MICs of sedecamycin against 79 field isolates of T. hyodysenteriae ranged from 0.78 to 12.5 micrograms/ml, the MIC for 90% of the strains tested (MIC90)
L Beutin et al.
Antimicrobial agents and chemotherapy, 20(3), 336-343 (1981-09-01)
The quinoxaline-di-N-oxides carbadox, olaquindox, and quindoxin, which are potent antibacterial agents, were tested for mutagenicity in the Salmonella microsomal system. They all induced base pair substitutions and frameshift mutations in Salmonella, and occurred independently of the presence of a rat
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