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Merck
CN

C7002

Z-Val-Phe

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关于此项目

经验公式(希尔记法):
C22H26N2O5
化学文摘社编号:
分子量:
398.45
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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storage temp.

−20°C

SMILES string

O=C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)OCC2=CC=CC=C2

InChI

1S/C22H26N2O5/c1-15(2)19(24-22(28)29-14-17-11-7-4-8-12-17)20(25)23-18(21(26)27)13-16-9-5-3-6-10-16/h3-12,15,18-19H,13-14H2,1-2H3,(H,23,25)(H,24,28)(H,26,27)

InChI key

XINBRUNUJFZFGH-UHFFFAOYSA-N



存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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V Kohli et al.
Gastroenterology, 116(1), 168-178 (1998-12-31)
Calpain proteases have been implicated in cell death by necrosis and more recently by apoptosis. Experiments were designed to determine the role of calpain proteases in ischemic rat liver injury by measurement of cytosolic calpain activity after different periods of
D Sindram et al.
Transplantation, 68(1), 136-140 (1999-07-31)
Cold preservation of the liver followed by reperfusion results in sinusoidal endothelial cell (SEC) apoptosis. Calpain-like activity is dramatically increased during reperfusion and inhibition of calpains results in lower graft injury and longer survival. Recently, calpains have been implicated in
Heike Weber et al.
International journal of experimental pathology, 90(4), 387-399 (2009-08-08)
The cytosolic cysteine protease calpain is implicated in a multitude of cellular functions but also plays a role in cell damage. Our previous results suggest that an activation of calpain accompanied by a decrease in its endogenous inhibitor calpastatin may