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C7039

Cefotaxime sodium salt 钠盐

Name: Cefotaxime sodium salt 钠盐
Brand: SIGMA

powder or crystals, suitable for plant cell culture, BioReagent

别名:

Cefotaxim sodium salt 钠盐

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₆N₅NaO₇S₂

化学文摘社编号:

64485-93-4

分子量:

477.45

NACRES:

NA.72

PubChem Substance ID:

24892923

UNSPSC Code:

10171502

EC Number:

264-915-9

MDL number:

MFCD00079073

Beilstein/REAXYS Number:

5711411

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产品名称

Cefotaxime sodium salt 钠盐, suitable for plant cell culture, BioReagent, powder or crystals

product line

BioReagent

Quality Level

200

form

powder or crystals

technique(s)

cell culture | plant: suitable

color

off-white to pale yellow

solubility

H₂O: 10% ( )

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

agriculture

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

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General description

Chemical structure: β-lactam

Application

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

Biochem/physiol Actions

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.

Mode of Action: Inhibits bacterial cell wall synthesis.

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000547480

0000478169

0000451286

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Bacterial nanoscale cultures for phenotypic multiplexed antibiotic susceptibility testing

Weibull E, et al.

Journal of Clinical Microbiology, 52(9), 3310-3317 (2014)

Antibiogram and beta-lactamase genes among cefotaxime resistant E. coli from wastewater treatment plant.

Anthony Ayodeji Adegoke et al.

Antimicrobial resistance and infection control, 9(1), 46-46 (2020-03-14)

The World Health Organization (WHO) recently classified Enterobacteriaceae resistance to third-generation cephalosporin into the group of pathogens with critical criteria for future research. A study to assess the antibiogram and beta-lactamase genes among the cefotaxime resistant E. coli (CREc) from

Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use.

AA C, et al.

Drugs (1983)

Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri

Hirth M, et al.

Metabolomics, 13(9), 68-68 (2017)

Unveiling the presence of biosynthetic pathways for bioactive compounds in the Thalassiosira rotula transcriptome.

Valeria Di Dato et al.

Scientific reports, 9(1), 9893-9893 (2019-07-11)

Diatoms are phytoplankton eukaryotic microalgae that are widely distributed in the world's oceans and are responsible for 20-25% of total carbon fixation on the planet. Using transcriptome sequencing here we show for the first time that the ubiquitous diatom Thalassiosira

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实验方案

Antibiotics in Plant Tissue Culture Protocol

Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.

全球贸易项目编号

货号	GTIN
C7039-100MG	04061835568284
C7039-1G	04061835509621
C7039-10G	04061835568291
C7039-500MG	04061835568307
C7039-5G	04061835568314

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