产品名称
N-[2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl]-3-methoxybenzamide, solid
SMILES string
COc1cccc(c1)C(=O)NCCN2CCN(CC2)c3ccc(Cl)cc3
form
solid
solubility
DMSO: 22 mg/mL
H2O: insoluble
Gene Information
human ... DRD2(1813), DRD4(1815)
rat ... Adra1a(29412), Drd3(29238), Htr1a(24473)
Biochem/physiol Actions
Potent, selective D4 dopamine receptor ligand.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
R Perrone et al.
Journal of medicinal chemistry, 43(2), 270-277 (2000-01-29)
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide (1), a high-affinity and selective dopamine D(4) receptor ligand, was chosen as a lead, and structural modifications were done on its amide bond and on its alkyl chain linking the benzamide moiety to the piperazine ring and by preparing
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