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Merck
CN

C7344

Sigma-Aldrich

环二磷酸腺苷核酸糖

≥90% (HPLC), from Ovotestis from sea hare, lyophilized powder

别名:

ADP-环[N1:1′′]-核糖, cADP-核酸糖, cADPR, 环ADPR

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关于此项目

经验公式（希尔记法）:
C15H21N5O13P2
CAS Number:
119340-53-3
分子量:
541.30
MDL编号:
MFCD00214262
UNSPSC代码:
41106305
NACRES:
NA.51

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Product Name

环二磷酸腺苷核酸糖, ≥90% (HPLC), lyophilized powder

生物来源

(Ovotestis from sea hare)

质量水平

200

方案

≥90% (HPLC)

表单

lyophilized powder

溶解性

water: 5 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

O[C@H]1[C@@H](O)[C@H]2O[C@@H]1COP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)[n@H]4cnc5C(=N)[N@@H]2C=Nc45

InChI

1S/C15H21N5O13P2/c16-12-7-13-18-4-19(12)14-10(23)8(21)5(31-14)1-29-34(25,26)33-35(27,28)30-2-6-9(22)11(24)15(32-6)20(13)3-17-7/h3-6,8-11,14-16,21-24H,1-2H2,(H,25,26)(H,27,28)/t5-,6-,8-,9-,10-,11-,14-,15-/m1/s1

InChI key

BQOHYSXSASDCEA-KEOHHSTQSA-N

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相关类别

应用

环状二磷酸腺苷核糖已被用于刺激星形胶质细胞激活 CD38 信号。它也被用于缓冲蛋白胨水的补充，以恢复肠炎链球菌。
环腺苷二磷酸核糖（cADPR）是细胞内第二信使，其通过兰尼碱受体调动细胞内 Ca2+ 从肌质网中释放。CADPR 也是葡萄糖诱导内分泌胰腺释放胰岛素以及植物中脱落酸诱导的钙释放的第二信使。

生化/生理作用

调动细胞内 Ca2+；调节由兰尼碱特异性阻断的 Ca2+诱导的 Ca2+ 释放；葡萄糖诱导胰岛素从内分泌胰腺释放以及植物中脱落酸诱导钙释放的第二信使。

包装

根据核苷酸含量确定包装尺寸。

外形

冻干粉末

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000452465
0000452465
0000448017
0000448017
0000433616

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