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Merck
CN

C7344

环二磷酸腺苷核酸糖

≥90% (HPLC), from Ovotestis from sea hare, lyophilized powder

别名:

ADP-环[N1:1′′]-核糖, cADP-核酸糖, cADPR, 环ADPR

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关于此项目

经验公式（希尔记法）:
C15H21N5O13P2
化学文摘社编号:
119340-53-3
分子量:
541.30
MDL number:
MFCD00214262
UNSPSC Code:
41106305
NACRES:
NA.51
Assay:
≥90% (HPLC)
Biological source:
(Ovotestis from sea hare)
Form:
lyophilized powder
Solubility:
water: 5 mg/mL, clear, colorless
Storage temp.:
−20°C

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产品名称

环二磷酸腺苷核酸糖, ≥90% (HPLC), lyophilized powder

SMILES string

O[C@H]1[C@@H](O)[C@H]2O[C@@H]1COP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)[n@H]4cnc5C(=N)[N@@H]2C=Nc45

InChI

1S/C15H21N5O13P2/c16-12-7-13-18-4-19(12)14-10(23)8(21)5(31-14)1-29-34(25,26)33-35(27,28)30-2-6-9(22)11(24)15(32-6)20(13)3-17-7/h3-6,8-11,14-16,21-24H,1-2H2,(H,25,26)(H,27,28)/t5-,6-,8-,9-,10-,11-,14-,15-/m1/s1

InChI key

BQOHYSXSASDCEA-KEOHHSTQSA-N

biological source

(Ovotestis from sea hare)

assay

≥90% (HPLC)

form

lyophilized powder

solubility

water: 5 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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相关类别

Application

环状二磷酸腺苷核糖已被用于刺激星形胶质细胞激活 CD38 信号。它也被用于缓冲蛋白胨水的补充，以恢复肠炎链球菌。
环腺苷二磷酸核糖（cADPR）是细胞内第二信使，其通过兰尼碱受体调动细胞内 Ca2+ 从肌质网中释放。CADPR 也是葡萄糖诱导内分泌胰腺释放胰岛素以及植物中脱落酸诱导的钙释放的第二信使。

Biochem/physiol Actions

调动细胞内 Ca2+；调节由兰尼碱特异性阻断的 Ca2+诱导的 Ca2+ 释放；葡萄糖诱导胰岛素从内分泌胰腺释放以及植物中脱落酸诱导钙释放的第二信使。

Packaging

根据核苷酸含量确定包装尺寸。

Physical form

冻干粉末

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000521657
0000521657
0000502823
0000502823
0000483204

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