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Merck
CN

C7518

Sigma-Aldrich

L -肉碱 盐酸盐

≥97%, from equine muscle

别名:

(-)-β-羟基-γ-(三甲铵)丁酸, 维生素 BT

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关于此项目

线性分子式:
(CH3)3N+CH2CH(OH)CH2CO2H · Cl-
CAS Number:
分子量:
197.66
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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生物来源

equine muscle

方案

≥97%

储存温度

−20°C

SMILES字符串

[Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O

InChI

1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1

InChI key

JXXCENBLGFBQJM-FYZOBXCZSA-N

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生化/生理作用

肉毒碱是季铵,天然存在于大多数哺乳动物组织中。它在骨骼肌和心脏中参与能量代谢调控,浓度相对较高。它可将葡萄糖代谢由糖酵解转移至糖原储存,并促进长链脂肪酸向线粒体转运,使其在线粒体氧化产生能量。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cell metabolism, 29(6), 1258-1273 (2019-04-02)
The basis for region-specific neuronal toxicity in Huntington disease is unknown. Here, we show that region-specific neuronal vulnerability is a substrate-driven response in astrocytes. Glucose is low in HdhQ(150/150) animals, and astrocytes in each brain region adapt by metabolically reprogramming
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Canadian journal of physiology and pharmacology, 93(11), 913-922 (2015-09-26)
We have shown that reduced expression of receptor-interacting protein 140 (RIP140) alters the regulation of fatty-acid (FA) oxidation in muscle. To determine whether a high level of FA availability alters the effects of RIP140 on metabolic regulation, L6 myotubes were
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The aim of present study was to investigate the effects of ammonium ions on in vitro neuronal network activity and to search alternative methods of acute ammonia neurotoxicity prevention. Rat hippocampal neuronal and astrocytes co-cultures in vitro, fluorescent microscopy and

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