C7527
氯化胆碱
BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%
别名:
(2-羟乙基)三甲基氯化铵
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关于此项目
线性分子式:
(CH3)3N(Cl)CH2CH2OH
化学文摘社编号:
分子量:
139.62
Beilstein:
3563126
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.75
生物来源
synthetic (organic)
质量水平
产品线
BioReagent
方案
≥98%
表单
crystals
分子量
Mw 139.62 g/mol
技术
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
颜色
white
pH值（酸碱度）
5.0-6.5 (25 °C, 140 g/L)
mp
302-305 °C (dec.) (lit.)
溶解性
H2O: 50 mg/mL
SMILES字符串
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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一般描述
氯化胆碱是一种季铵盐，与氢键供体(HBD)缔合。它是许多重要生理功能必不可少的成分，用作营养添加剂。胆碱是甲基转移反应的甲基来源。
胆碱乙酰基转移酶底物
应用
氯化胆碱已用于：
- 用作胆碱乙酰基转移酶 (ChAT)缓冲液组分，用于培养人成神经细胞瘤（SK-N-SH）细胞中的胆碱吸收
- 生成胆碱标准曲线，以定量磷脂酶D (PLD)活性
- 用作解剖内海马脑切片的切片溶液组分
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Harvie P Portugaliza et al.
Scientific reports, 9(1), 14595-14595 (2019-10-12)
Transmission of malaria parasites from humans to mosquito vectors requires that some asexual parasites differentiate into sexual forms termed gametocytes. The balance between proliferation in the same host and conversion into transmission forms can be altered by the conditions of
Choline: an essential nutrient for public health
Zeisel SH and Da Costa KA
Nutr. Rev, 67(11), 615-623 (2009)
Synthesis and characterization of choline chloride based binary mixtures
Abbas Q and Binder L
ECS Transactions, 33(7), 49-59 (2010)
Determination of high-affinity choline uptake (HACU) and choline acetyltransferase (ChAT) activity in the same population of cultured cells
Ray B, et al.
Brain Research, 1297(11), 160-168 (2009)
Zhenglin Gu et al.
Cell reports, 31(10), 107740-107740 (2020-06-11)
Muscarinic acetylcholine receptors (mAChRs) are critically involved in hippocampal theta generation, but much less is known about the role of nicotinic AChRs (nAChRs). Here we provide evidence that α7 nAChRs expressed on interneurons, particularly those in oriens lacunosum moleculare (OLM)
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