产品名称
伴刀豆球蛋白A 来源于洋刀豆 （刀豆）, agarose conjugate, Type VI, saline suspension
biological source
Canavalia ensiformis
conjugate
agarose conjugate
type
Type VI
form
saline suspension
extent of labeling
≥15 mg concanavalin A protein per mL
matrix
cross-linked 4% beaded agarose
matrix activation
cyanogen bromide
matrix attachment
amino
matrix spacer
1 atom
storage temp.
2-8°C
Quality Level
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Analysis Note
在报道中，凝集活性以μg/ml表示，并且是在含有1mg/mL Ca 2+和Mn 2+的磷酸盐缓冲盐水(pH 6.8)的系列稀释液中进行测定的。该活性是在25℃孵育1小时后，对2％人红细胞悬浮液进行凝集所需的最低浓度。
Application
伴刀豆球蛋白A（Con A）已用于酶的固定化。
用于纯化含甘露糖的糖蛋白。
Biochem/physiol Actions
伴刀豆球蛋白A（Con A）是一种T细胞有丝分裂原，可激活淋巴细胞。
Con A可通过自噬诱导肿瘤细胞死亡。
Con A可通过自噬诱导肿瘤细胞死亡。
刀豆素 A 无血型特异性，但对末端 α-D-甘露糖基和 α-D-葡糖基残基具有亲和力。需要 Ca2+ 和 Mn2+ 离子存在才能显示活性。刀豆素 A 在 pH 6.5 或更低的条件下解离为二聚体。pH 在 5.8 至 7.0 之间时，刀豆素 A 以四聚体形式存在；pH 高于 7.0 时，形成更高的聚合体。根据聚合程度不同，刀豆素 A 可能显示出具有促有丝分裂的活性。琥珀酰化可以生成一种能够在 pH 高于 5.6 时仍保持二聚体形式的活性二聚体。
General description
从刀豆（Canavalia ensiformis）中分离的伴刀豆球蛋白A（Con A）是甘露糖或葡萄糖特异性结合凝集素。凝集素是四聚体，每个亚基都具有糖结合位点。Con A可以通过葡萄聚糖亲和层析分离。
Physical form
悬浮于1.0 M NaCl+0.1 M磷酸钾，pH值6.0中，含1 mM CaCl2、1 mM MgCl2和1 mM MnCl2，含防腐剂
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
动植物源性产品
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