C7745
CDK7/Cyclin H1/MNAT1, active, His tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
CAK, CCNH, CDKN7, MAT1, P39mo15, RNF66, STK1, p34, p37
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
17-22 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
recombinant
expressed in baculovirus infected Sf9 cells
product line
PRECISIO® Kinase
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
17-22 nmol/min·mg
mol wt
CDK7 subunit ~40 kDa, MNAT1 subunit ~37 kDa, cyclin D1 ~39 kDa
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CCNH(902), CDK7(1022), MNAT1(4331)
Biochem/physiol Actions
CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Physical form
Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
警示词
Danger
危险代码
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
怎么回事？
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)