C7821
Curdlan
from Alcaligenes faecalis, ≥98% (TLC), solid
别名:
β-1,3-葡聚糖 水合物
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关于此项目
Form:
solid
Quality level:
General description
凝胶多糖是一种线性结构的不溶性天然聚合物，主要由粪产碱菌产生。它是一种具有明胶特性的膳食纤维。
Application
来自粪产碱菌的凝胶多糖已用于：
- 刺激鲤鱼巨噬细胞，以调节差异表达基因
- 刺激人肠上皮细胞分泌细胞因子
- 研究其对小鼠肺泡巨噬细胞炎症/呼吸爆发相关基因转录反应的影响
- 在β-1,3–1,4-葡聚糖酶活性检测中用作底物
Biochem/physiol Actions
凝胶多糖在食品工业中=用作食品添加剂。它可以提高羟基磷灰石/壳聚糖支架的弹性，降低了易脆性，有助于骨再生。
热凝胶多糖是一种（1,3）-β-葡聚糖。它是由受体dectin-1识别的病原体相关分子模式（PAMP）。激活的dectin-1与TLR2/TLR6一起可促进信号传导，导致促炎细胞因子的产生，从而诱导炎症。
Preparation Note
对于70℃条件下的凝胶化，氢氧化钠的浓度应为0.01M。
经测试，本品可溶于0.1N氢氧化钠，浓度9.8 - 10.2 mg/mL。溶解时一般需要加热和/或超声处理。该产品并不无菌。用于细胞培养时，使用前应将储备液过滤除菌。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
Jing Li et al.
Applied microbiology and biotechnology, 97(19), 8495-8503 (2013-07-31)
Biologically active β-1,3-oligosaccharides with rapidly growing biomedical applications are produced from hydrolysis of curdlan polysaccharide. The water-insoluble curdlan impedes its hydrolysis efficiency which is enhanced by our newly developed alkali-neutralization treatment process to increase the stability of curdlan suspension to
Nicola Jackson et al.
European journal of immunology, 44(4), 962-969 (2014-01-25)
Type B T cells recognize peptide-MHC class II (pMHCII) isoforms that are structurally distinct from those recognized by conventional type A T cells. These alternative type B conformers result from peptide loading in the absence of HLA-DM. Type A conformers
Microbial exopolisaccharides for biomedical applications
Journal of Material Science & Engineering, 165-219 (2019)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C7821-5G | 04061833521212 |