C8138
氯丙嗪 盐酸盐
≥98% (TLC), powder, D2 dopamine receptor antagonist
别名:
2-氯-10-(3-二甲氨基丙基)吩噻嗪 盐酸盐, CPZ, 氯普马嗪
并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C17H19ClN2S · HCl
化学文摘社编号:
分子量:
355.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-701-3
MDL number:
Beilstein/REAXYS Number:
3779989
Assay:
≥98% (TLC)
Form:
powder
产品名称
氯丙嗪 盐酸盐, ≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
form
powder
mp
194-196 °C
solubility
water: 50 mg/mL
originator
GlaxoSmithKline
SMILES string
Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
InChI
1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key
FBSMERQALIEGJT-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HTR2A(3356)
Application
Chlorpromazine hydrochloride has been used:
- as an antagonists for calmodulin kinase
- as a medium supplement to test its cytotoxic effects in human lung microvascular endothelial cells (HMVEC-L)
- as an inhibitor of clathrin-mediated endocytosis in RAW 264.7 cells
在血红蛋白和过氧化物酶的微量测定中替代联苯胺、邻联茴香胺和邻联甲苯胺。
Biochem/physiol Actions
吩噻嗪类抗精神病药;D2 多巴胺受体拮抗剂，H1 组胺受体拮抗剂;抑制钙调蛋白依赖性环核苷酸磷酸二酯酶和一氧化氮合成酶的活化。
氯丙嗪表现出对白血病细胞的细胞毒性和抗增殖活性，但是不会影响正常淋巴细胞的活力。
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Still not finding the right product?
Explore all of our products under 氯丙嗪 盐酸盐
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 3 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges