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Merck
CN

C8988

8-(4-氯苯硫基)-2′-O-甲基腺苷- 3′,5′-环一磷酸 单钠 水合物

≥98% (HPLC), Epac or cAMP-GEF activator, powder

别名:

8-pCPT-2′-O-Me-cAMP

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关于此项目

经验公式(希尔记法):
C17H16N5O6ClPSNa · xH2O
化学文摘社编号:
分子量:
507.82 (anhydrous basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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产品名称

8-(4-氯苯硫基)-2′-O-甲基腺苷- 3′,5′-环一磷酸 单钠 水合物, ≥98% (HPLC)

SMILES string

O.[Na+].CO[C@@H]1[C@@H]2OP([O-])(=O)OC[C@H]2O[C@H]1n3c(Sc4ccc(Cl)cc4)nc5c(N)ncnc35

InChI key

NVPSOXGMFVFZIS-IPBMGFFTSA-M

InChI

1S/C17H17ClN5O6PS.Na.H2O/c1-26-13-12-10(6-27-30(24,25)29-12)28-16(13)23-15-11(14(19)20-7-21-15)22-17(23)31-9-4-2-8(18)3-5-9;;/h2-5,7,10,12-13,16H,6H2,1H3,(H,24,25)(H2,19,20,21);;1H2/q;+1;/p-1/t10-,12-,13-,16-;;/m1../s1

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white

mp

235.5-237.5 °C (lit.)

solubility

H2O: >10 mg/mL

storage temp.

−20°C

Quality Level

Other Notes

光敏感

Biochem/physiol Actions

天然cAMP的类似物,Epac或cAMP-GEF的强效和特异性膜透过活化剂,是环磷酸腺苷的一种新受体。
天然cAMP的类似物,由cAMP(Epac或cAMP-GEF)直接激活的交换因子的强效和特异性膜透过活化剂,是环磷酸腺苷的一种新受体

Features and Benefits

这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

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